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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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ACTBL2
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CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

CANCER ATLAS

Gene description

Actin, beta-like 2

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Lymphoma

STAINING SUMMARY

HPA041264
HPA041271

Tissue

Cancer staining

Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Tissue

Cancer staining

Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary

A majority of cancer tissues showed moderate to strong membranous and/or cytoplasmic positivity.

Tissue

Cancer staining

Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Tissue

Cancer staining

Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary

Colorectal, ovarian, endometrial, testicular, breast, urothelial, pancreatic and liver cancers displayed moderate to strong membranous staining. Malignant lymphomas exhibited moderate to strong cytoplasmic positivity. Remaining cancer tissues were weakly stained or negative.

GENE INFORMATION

Gene name

ACTBL2 (HGNC Symbol)

Synonyms

DKFZp686D0972

Description

Actin, beta-like 2 (HGNC Symbol)

Entrez gene summary

Chromosome

5

Cytoband

q11.2

Chromosome location (bp)

57480016 - 57482809

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000169067 (version 83.38)

Entrez gene

345651

UniProt

Q562R1 (UniProt - Evidence at protein level)

neXtProt

NX_Q562R1

Antibodypedia

ACTBL2 antibodies

PROTEIN BROWSER

ACTBL2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACTBL2-001
ENSP00000416706
ENST00000423391
Q562R1 [Direct mapping]
Beta-actin-like protein 2
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005524 [ATP binding]
GO:0005615 [extracellular space]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0008150 [biological_process]
GO:0070062 [extracellular exosome]
Show all
376 aa
42 kDa
No 0

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The Human Protein Atlas project is funded
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