Tissue expression of HSPB3 - Summary - The Human Protein Atlas

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HSPB3

TISSUE

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CELL

CANCER

TISSUE ATLAS

GENE/PROTEIN

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	HSPB3
Gene description	Heat shock 27kDa protein 3
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (heart muscle, skeletal muscle)
GTEx:	Group enriched (heart muscle, skeletal muscle)
FANTOM5:	Group enriched (heart muscle, skeletal muscle)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (heart muscle, skeletal muscle)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (heart muscle, skeletal muscle)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (heart muscle, skeletal muscle)

GENE INFORMATION
Gene name	HSPB3 (HGNC Symbol)
Synonyms	HSPL27
Description	Heat shock 27kDa protein 3 (HGNC Symbol)
Entrez gene summary	This gene encodes a muscle-specific small heat shock protein. A mutation in this gene is the cause of autosomal dominant distal hereditary motor neuropathy type 2C.[provided by RefSeq, Sep 2010]
Chromosome	5
Cytoband	q11.2
Chromosome location (bp)	54455601 - 54456384
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000169271 (version 83.38)
Entrez gene	8988
UniProt	Q12988 (UniProt - Evidence at protein level)
neXtProt	NX_Q12988
Antibodypedia	HSPB3 antibodies

PROTEIN BROWSER

HSPB3-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HSPB3-001 ENSP00000303394 ENST00000302005	Q12988 [Direct mapping] Heat shock protein beta-3 Q6ICS9 [Target identity:100%; Query identity:100%] HSPB3 protein; Heat shock 27kDa protein 3; cDNA, FLJ94950, Homo sapiens heat shock 27kDa protein 3 (HSPB3), mRNA Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006986 [response to unfolded protein] Show all	150 aa 17 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.