Expression of PDILT in cancer - Summary

CANCER ATLAS

Gene description

Protein disulfide isomerase-like, testis expressed

Protein class

Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA041913

Tissue	Cancer staining	Protein expression of normal tissue
Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma

Tissue	Cancer staining	Protein expression of normal tissue
Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary	Weak to moderate cytoplasmic and/or nuclear immunoreactivity was observed in the majority of malignant melanomas, lung and thyroid cancers along with a few liver cancers. Other malignancies were in general negative.

GENE INFORMATION
Gene name	PDILT (HGNC Symbol)
Synonyms	PDIA7
Description	Protein disulfide isomerase-like, testis expressed (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p12.3
Chromosome location (bp)	20359170 - 20404737
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000169340 (version 83.38)
Entrez gene	204474
UniProt	Q8N807 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N807
Antibodypedia	PDILT antibodies

PROTEIN BROWSER

PDILT-001	PDILT-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PDILT-001 ENSP00000305465 ENST00000302451	Q8N807 [Direct mapping] Protein disulfide-isomerase-like protein of the testis Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Show all	GO:0003756 [protein disulfide isomerase activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0006457 [protein folding] GO:0007275 [multicellular organismal development] GO:0007286 [spermatid development] GO:0008152 [metabolic process] GO:0016477 [cell migration] GO:0031545 [peptidyl-proline 4-dioxygenase activity] GO:0045454 [cell redox homeostasis] Show all	584 aa 66.7 kDa	Yes	0
PDILT-002 ENSP00000459161 ENST00000575561	I3L1W7 [Direct mapping] Protein disulfide-isomerase-like protein of the testis Show all	THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0003756 [protein disulfide isomerase activity] GO:0006457 [protein folding] GO:0031545 [peptidyl-proline 4-dioxygenase activity] Show all	177 aa 19.2 kDa	Yes	0