Tissue expression of SPRR1A - Summary - The Human Protein Atlas

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SPRR1A

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TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	SPRR1A
Gene description	Small proline-rich protein 1A
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (esophagus)
GTEx:	Tissue enhanced (esophagus, vagina)
FANTOM5:	Tissue enriched (esophagus)

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in squamous epithelia.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 1 antibody. CAB011237
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

N/A

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (esophagus)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (esophagus, vagina)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (esophagus)

GENE INFORMATION
Gene name	SPRR1A
Synonyms
Description	Small proline-rich protein 1A (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q21.3
Chromosome location (bp)	152985231 - 152985500
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000169474 (version 83.38)
Entrez gene	6698
UniProt	P35321 (UniProt - Evidence at protein level)
neXtProt	NX_P35321
Antibodypedia	SPRR1A antibodies

PROTEIN BROWSER

SPRR1A-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SPRR1A-001 ENSP00000357751 ENST00000368762	P35321 [Direct mapping] Cornifin-A Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001533 [cornified envelope] GO:0005198 [structural molecule activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0008544 [epidermis development] GO:0018149 [peptide cross-linking] GO:0030216 [keratinocyte differentiation] GO:0030674 [protein binding, bridging] GO:0031424 [keratinization] Show all	89 aa 9.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.