Cell atlas - ZNF280A - The Human Protein Atlas

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ZNF280A

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	ZNF280A
Gene description	Zinc finger protein 280A
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Cell line enhanced (K-562, BEWO, SK-MEL-30)
Protein evidence	Evidence at transcript level
Main location	Localized to the Nucleoplasm (uncertain)

DATA RELIABILITY
Reliability score	Uncertain based on 1 antibody. HPA044475
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (K-562, BEWO, SK-MEL-30) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA044475	A-431	Nucleoplasm
	HPA044475	U-2 OS	Nucleoplasm
	HPA044475	U-251 MG	Nucleoplasm

GENE INFORMATION
Gene name	ZNF280A (HGNC Symbol)
Synonyms	3'OY11.1, SUHW1, ZNF280, ZNF636
Description	Zinc finger protein 280A (HGNC Symbol)
Entrez gene summary	This gene encodes a zinc finger protein. The encoded protein contains 4 C2H2-type zinc fingers, which are commonly found in transcription factors. A variety of functions may be performed by this type of zinc finger protein, including the binding of DNA or RNA. [provided by RefSeq, Apr 2014]
Chromosome	22
Cytoband	q11.22
Chromosome location (bp)	22513736 - 22520270
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000169548 (version 83.38)
Entrez gene	129025
UniProt	P59817 (UniProt - Evidence at transcript level)
neXtProt	NX_P59817
Antibodypedia	ZNF280A antibodies

PROTEIN BROWSER

ZNF280A-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF280A-001 ENSP00000302855 ENST00000302097	P59817 [Direct mapping] Zinc finger protein 280A Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] Show all	542 aa 60.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.