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PROKR1

GENERAL INFORMATION

Gene name

 PROKR1

Gene description

 Prokineticin receptor 1

Protein class

 G-protein coupled receptors
Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (epididymis, adipose tissue, adrenal gland)
GTEx:Tissue enhanced (testis)

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous cytoplasmic expression

DATA RELIABILITY

Data reliability
description

 Antibody staining not consistent with RNA expression data. Caution, targets protein from more than one gene.

Reliability score

 Uncertain based on 1 antibody.
HPA029396
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (epididymis, adipose tissue, adrenal gland)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis)

GENE INFORMATION

Gene name

 PROKR1 (HGNC Symbol)

Synonyms

 GPR73, GPR73a, PKR1, ZAQ

Description

 Prokineticin receptor 1 (HGNC Symbol)

Entrez gene summary

Chromosome

 2

Cytoband

 p13.3

Chromosome location (bp)

 68643589 - 68658247

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000169618 (version 83.38)

Entrez gene

UniProt

 Q8TCW9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8TCW9

Antibodypedia

 PROKR1 antibodies

PROTEIN BROWSER
PROKR1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PROKR1-001
ENSP00000303775
ENST00000303786
Q8TCW9 [Direct mapping]
Prokineticin receptor 1
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G-protein coupled receptors
   GPCRs excl olfactory receptors
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
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GO:0004930 [G-protein coupled receptor activity]
GO:0004983 [neuropeptide Y receptor activity]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0007166 [cell surface receptor signaling pathway]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007218 [neuropeptide signaling pathway]
GO:0007623 [circadian rhythm]
GO:0016021 [integral component of membrane]
GO:0043066 [negative regulation of apoptotic process]
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 393 aa
44.8 kDa 		No 7

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.