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Most normal tissues showed weak to moderate cytoplasmic staining with additional nuclear positivity in many cases. Purkinje cells exhibited strong immunoreactivity. Lymphoid tissues, soft tissues, liver, kidney and follicles in ovary were generally negative.
HPA049497
Neuronal cells of cerebral cortex, glial cells and stomach displayed strong cytoplasmic staining. Neuropil, renal tubules, islets of Langerhans, testis, vagina and skeletal muscle cells were moderately positive. Remaining normal tissues were weakly stained or negative.
HPA051675
Subsets of lymphoid cells and the keratinized squamous epithelium showed distinct cytoplasmic positivity. The heart showed moderate additional membranous positivity. Subsets of cells in seminiferus ducts showed moderate nuclear positivity. Normal tissues in general showed weak cytoplasmic staining or were negative.