Cell atlas - MUC17 - The Human Protein Atlas

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MUC17

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TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	MUC17
Gene description	Mucin 17, cell surface associated
Protein class	Cancer-related genes Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	MUC17
Synonyms
Description	Mucin 17, cell surface associated (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a membrane-bound mucin that provides protection to gut epithelial cells. The encoded protein contains about 60 tandem repeats, with each repeat being around 60 aa. N-glycosylation enables the encoded protein to localize on the cell surface, while the C-terminus interacts with the scaffold protein PDZ domain containing 1 (PDZK1). Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015]
Chromosome	7
Cytoband	q22.1
Chromosome location (bp)	101020072 - 101058745
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000169876 (version 83.38)
Entrez gene	140453
UniProt	Q685J3 (UniProt - Evidence at protein level)
neXtProt	NX_Q685J3
Antibodypedia	MUC17 antibodies

PROTEIN BROWSER

MUC17-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MUC17-001 ENSP00000302716 ENST00000306151	Q685J3 [Direct mapping] Mucin-17 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Cancer-related genes Mutated cancer genes Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0005796 [Golgi lumen] GO:0005902 [microvillus] GO:0006493 [protein O-linked glycosylation] GO:0009897 [external side of plasma membrane] GO:0016021 [integral component of membrane] GO:0016266 [O-glycan processing] GO:0016324 [apical plasma membrane] GO:0019725 [cellular homeostasis] GO:0030165 [PDZ domain binding] GO:0030197 [extracellular matrix constituent, lubricant activity] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] Show all	4493 aa 451.7 kDa	Yes	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.