Expression of TAS1R3 in cancer - Summary

CANCER ATLAS

Gene description

Taste receptor, type 1, member 3

Protein class

G-protein coupled receptors, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA053439

GENE INFORMATION
Gene name	TAS1R3 (HGNC Symbol)
Synonyms	T1R3
Description	Taste receptor, type 1, member 3 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a G-protein coupled receptor involved in taste responses. The encoded protein can form a heterodimeric receptor with TAS1R1 to elicit the umami taste response, or it can bind with TAS1R2 to form a receptor for the sweet taste response. [provided by RefSeq, Nov 2015]
Chromosome	1
Cytoband	p36.33
Chromosome location (bp)	1331314 - 1335306
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000169962 (version 83.38)
Entrez gene	83756
UniProt	Q7RTX0 (UniProt - Evidence at protein level)
neXtProt	NX_Q7RTX0
Antibodypedia	TAS1R3 antibodies

PROTEIN BROWSER

TAS1R3-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TAS1R3-001 ENSP00000344411 ENST00000339381	Q7RTX0 [Direct mapping] Taste receptor type 1 member 3 Show all	Family 3 (C) receptors G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0001582 [detection of chemical stimulus involved in sensory perception of sweet taste] GO:0004930 [G-protein coupled receptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0008527 [taste receptor activity] GO:0016021 [integral component of membrane] GO:0033041 [sweet taste receptor activity] GO:0046982 [protein heterodimerization activity] GO:0050916 [sensory perception of sweet taste] GO:0050917 [sensory perception of umami taste] GO:1903767 [sweet taste receptor complex] Show all	852 aa 93.4 kDa	Yes	7