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SIK2

CANCER ATLAS

Gene description

 Salt-inducible kinase 2

Protein class

 Enzymes, Predicted membrane proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA016026

GENE INFORMATION

Gene name

 SIK2 (HGNC Symbol)

Synonyms

 DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2

Description

 Salt-inducible kinase 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 11

Cytoband

 q23.1

Chromosome location (bp)

 111602391 - 111730853

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000170145 (version 83.38)

Entrez gene

 23235

UniProt

 Q9H0K1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H0K1

Antibodypedia

 SIK2 antibodies

PROTEIN BROWSER
SIK2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SIK2-001
ENSP00000305976
ENST00000304987
Q9H0K1 [Direct mapping]
Serine/threonine-protein kinase SIK2
A0A024R3G7 [Target identity:100%; Query identity:100%]
SNF1-like kinase 2, isoform CRA_c
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Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CAMK Ser/Thr protein kinases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000287 [magnesium ion binding]
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006468 [protein phosphorylation]
GO:0008286 [insulin receptor signaling pathway]
GO:0035556 [intracellular signal transduction]
GO:0046626 [regulation of insulin receptor signaling pathway]
GO:0046777 [protein autophosphorylation]
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 926 aa
103.9 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.