Cell atlas - HOXD12 - The Human Protein Atlas

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HOXD12

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	HOXD12
Gene description	Homeobox D12
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (REH)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (REH) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	HOXD12 (HGNC Symbol)
Synonyms	HOX4H
Description	Homeobox D12 (HGNC Symbol)
Entrez gene summary	This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined. [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband	q31.1
Chromosome location (bp)	176099730 - 176101193
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170178 (version 83.38)
Entrez gene	3238
UniProt	P35452 (UniProt - Evidence at protein level)
neXtProt	NX_P35452
Antibodypedia	HOXD12 antibodies

PROTEIN BROWSER

HOXD12-001	HOXD12-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HOXD12-001 ENSP00000385586 ENST00000406506	P35452 [Direct mapping] Homeobox protein Hox-D12 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Show all	GO:0001501 [skeletal system development] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005667 [transcription factor complex] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007389 [pattern specification process] GO:0042733 [embryonic digit morphogenesis] GO:0043565 [sequence-specific DNA binding] Show all	270 aa 29 kDa	No	0
HOXD12-002 ENSP00000385132 ENST00000404162	B5MCD3 [Direct mapping] Homeobox D12, isoform CRA_a; Homeobox protein Hox-D12 Show all	Predicted intracellular proteins Show all	GO:0003677 [DNA binding] Show all	246 aa 25.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.