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UBB

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GENERAL INFORMATION

Gene name

 UBB

Gene description

 Ubiquitin B

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 8
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 UBB (HGNC Symbol)

Synonyms

 FLJ25987, MGC8385

Description

 Ubiquitin B (HGNC Symbol)

Entrez gene summary

 This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Chromosome

 17

Cytoband

 p11.2

Chromosome location (bp)

 16380798 - 16382745

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000170315 (version 83.38)

Entrez gene

 7314

UniProt

 P0CG47 (UniProt - Evidence at protein level)

neXtProt

 NX_P0CG47

Antibodypedia

 UBB antibodies

PROTEIN BROWSER
UBB-001
UBB-002
UBB-003
UBB-005
UBB-006
UBB-007
UBB-008
UBB-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
UBB-001
ENSP00000304697
ENST00000302182
P0CG47 [Direct mapping]
Polyubiquitin-B Ubiquitin
Q5U5U6 [Target identity:100%; Query identity:100%]
Ubiquitin B; Ubiquitin B, isoform CRA_a
Show all
Predicted intracellular proteins
Show all
GO:0000082 [G1/S transition of mitotic cell cycle]
GO:0000086 [G2/M transition of mitotic cell cycle]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0000187 [activation of MAPK activity]
GO:0000209 [protein polyubiquitination]
GO:0000278 [mitotic cell cycle]
GO:0000423 [macromitophagy]
GO:0000715 [nucleotide-excision repair, DNA damage recognition]
GO:0000724 [double-strand break repair via homologous recombination]
GO:0002223 [stimulatory C-type lectin receptor signaling pathway]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I]
GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005739 [mitochondrion]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005975 [carbohydrate metabolic process]
GO:0005978 [glycogen biosynthetic process]
GO:0006006 [glucose metabolic process]
GO:0006281 [DNA repair]
GO:0006283 [transcription-coupled nucleotide-excision repair]
GO:0006289 [nucleotide-excision repair]
GO:0006297 [nucleotide-excision repair, DNA gap filling]
GO:0006302 [double-strand break repair]
GO:0006351 [transcription, DNA-templated]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0006977 [DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest]
GO:0007141 [male meiosis I]
GO:0007144 [female meiosis I]
GO:0007166 [cell surface receptor signaling pathway]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007179 [transforming growth factor beta receptor signaling pathway]
GO:0007219 [Notch signaling pathway]
GO:0007220 [Notch receptor processing]
GO:0007249 [I-kappaB kinase/NF-kappaB signaling]
GO:0007254 [JNK cascade]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007411 [axon guidance]
GO:0007623 [circadian rhythm]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0008584 [male gonad development]
GO:0008585 [female gonad development]
GO:0010008 [endosome membrane]
GO:0010467 [gene expression]
GO:0010803 [regulation of tumor necrosis factor-mediated signaling pathway]
GO:0010939 [regulation of necrotic cell death]
GO:0010992 [ubiquitin homeostasis]
GO:0012501 [programmed cell death]
GO:0016032 [viral process]
GO:0016197 [endosomal transport]
GO:0016236 [macroautophagy]
GO:0019058 [viral life cycle]
GO:0019068 [virion assembly]
GO:0019082 [viral protein processing]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0019985 [translesion synthesis]
GO:0021888 [hypothalamus gonadotrophin-releasing hormone neuron development]
GO:0030512 [negative regulation of transforming growth factor beta receptor signaling pathway]
GO:0030666 [endocytic vesicle membrane]
GO:0031145 [anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process]
GO:0031398 [positive regulation of protein ubiquitination]
GO:0032479 [regulation of type I interferon production]
GO:0032480 [negative regulation of type I interferon production]
GO:0032481 [positive regulation of type I interferon production]
GO:0033209 [tumor necrosis factor-mediated signaling pathway]
GO:0033683 [nucleotide-excision repair, DNA incision]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0034220 [ion transmembrane transport]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0035872 [nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway]
GO:0036297 [interstrand cross-link repair]
GO:0038061 [NIK/NF-kappaB signaling]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042059 [negative regulation of epidermal growth factor receptor signaling pathway]
GO:0042276 [error-prone translesion synthesis]
GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I]
GO:0042769 [DNA damage response, detection of DNA damage]
GO:0042981 [regulation of apoptotic process]
GO:0043005 [neuron projection]
GO:0043025 [neuronal cell body]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043209 [myelin sheath]
GO:0043488 [regulation of mRNA stability]
GO:0044281 [small molecule metabolic process]
GO:0045087 [innate immune response]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0047497 [mitochondrion transport along microtubule]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048812 [neuron projection morphogenesis]
GO:0050852 [T cell receptor signaling pathway]
GO:0051092 [positive regulation of NF-kappaB transcription factor activity]
GO:0051403 [stress-activated MAPK cascade]
GO:0051436 [negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle]
GO:0051437 [positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition]
GO:0051439 [regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle]
GO:0051881 [regulation of mitochondrial membrane potential]
GO:0055085 [transmembrane transport]
GO:0060612 [adipose tissue development]
GO:0060613 [fat pad development]
GO:0061024 [membrane organization]
GO:0061136 [regulation of proteasomal protein catabolic process]
GO:0061418 [regulation of transcription from RNA polymerase II promoter in response to hypoxia]
GO:0070062 [extracellular exosome]
GO:0070266 [necroptotic process]
GO:0070423 [nucleotide-binding oligomerization domain containing signaling pathway]
GO:0070911 [global genome nucleotide-excision repair]
GO:0070987 [error-free translesion synthesis]
GO:0071456 [cellular response to hypoxia]
GO:0072520 [seminiferous tubule development]
GO:0075733 [intracellular transport of virus]
GO:0090090 [negative regulation of canonical Wnt signaling pathway]
GO:0090263 [positive regulation of canonical Wnt signaling pathway]
GO:0097009 [energy homeostasis]
GO:0097190 [apoptotic signaling pathway]
GO:0097300 [programmed necrotic cell death]
GO:1901214 [regulation of neuron death]
GO:1902255 [positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator]
GO:1902527 [positive regulation of protein monoubiquitination]
Show all
 229 aa
25.8 kDa 		No 0
UBB-002
ENSP00000379178
ENST00000395837
P0CG47 [Direct mapping]
Polyubiquitin-B Ubiquitin
Q5U5U6 [Target identity:100%; Query identity:100%]
Ubiquitin B; Ubiquitin B, isoform CRA_a
Show all
Predicted intracellular proteins
Show all
GO:0000082 [G1/S transition of mitotic cell cycle]
GO:0000086 [G2/M transition of mitotic cell cycle]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0000187 [activation of MAPK activity]
GO:0000209 [protein polyubiquitination]
GO:0000278 [mitotic cell cycle]
GO:0000423 [macromitophagy]
GO:0000715 [nucleotide-excision repair, DNA damage recognition]
GO:0000724 [double-strand break repair via homologous recombination]
GO:0002223 [stimulatory C-type lectin receptor signaling pathway]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I]
GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005739 [mitochondrion]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005975 [carbohydrate metabolic process]
GO:0005978 [glycogen biosynthetic process]
GO:0006006 [glucose metabolic process]
GO:0006281 [DNA repair]
GO:0006283 [transcription-coupled nucleotide-excision repair]
GO:0006289 [nucleotide-excision repair]
GO:0006297 [nucleotide-excision repair, DNA gap filling]
GO:0006302 [double-strand break repair]
GO:0006351 [transcription, DNA-templated]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0006977 [DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest]
GO:0007166 [cell surface receptor signaling pathway]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007179 [transforming growth factor beta receptor signaling pathway]
GO:0007219 [Notch signaling pathway]
GO:0007220 [Notch receptor processing]
GO:0007249 [I-kappaB kinase/NF-kappaB signaling]
GO:0007254 [JNK cascade]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007411 [axon guidance]
GO:0007623 [circadian rhythm]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010008 [endosome membrane]
GO:0010467 [gene expression]
GO:0010803 [regulation of tumor necrosis factor-mediated signaling pathway]
GO:0010939 [regulation of necrotic cell death]
GO:0012501 [programmed cell death]
GO:0016032 [viral process]
GO:0016197 [endosomal transport]
GO:0016236 [macroautophagy]
GO:0019058 [viral life cycle]
GO:0019068 [virion assembly]
GO:0019082 [viral protein processing]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0019985 [translesion synthesis]
GO:0030512 [negative regulation of transforming growth factor beta receptor signaling pathway]
GO:0030666 [endocytic vesicle membrane]
GO:0031145 [anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process]
GO:0031398 [positive regulation of protein ubiquitination]
GO:0032479 [regulation of type I interferon production]
GO:0032480 [negative regulation of type I interferon production]
GO:0032481 [positive regulation of type I interferon production]
GO:0033209 [tumor necrosis factor-mediated signaling pathway]
GO:0033683 [nucleotide-excision repair, DNA incision]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0034220 [ion transmembrane transport]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0035872 [nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway]
GO:0036297 [interstrand cross-link repair]
GO:0038061 [NIK/NF-kappaB signaling]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042059 [negative regulation of epidermal growth factor receptor signaling pathway]
GO:0042276 [error-prone translesion synthesis]
GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I]
GO:0042769 [DNA damage response, detection of DNA damage]
GO:0042981 [regulation of apoptotic process]
GO:0043005 [neuron projection]
GO:0043025 [neuronal cell body]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043488 [regulation of mRNA stability]
GO:0044281 [small molecule metabolic process]
GO:0045087 [innate immune response]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0047497 [mitochondrion transport along microtubule]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048812 [neuron projection morphogenesis]
GO:0050852 [T cell receptor signaling pathway]
GO:0051092 [positive regulation of NF-kappaB transcription factor activity]
GO:0051403 [stress-activated MAPK cascade]
GO:0051436 [negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle]
GO:0051437 [positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition]
GO:0051439 [regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle]
GO:0051881 [regulation of mitochondrial membrane potential]
GO:0055085 [transmembrane transport]
GO:0061024 [membrane organization]
GO:0061136 [regulation of proteasomal protein catabolic process]
GO:0061418 [regulation of transcription from RNA polymerase II promoter in response to hypoxia]
GO:0070062 [extracellular exosome]
GO:0070266 [necroptotic process]
GO:0070423 [nucleotide-binding oligomerization domain containing signaling pathway]
GO:0070911 [global genome nucleotide-excision repair]
GO:0070987 [error-free translesion synthesis]
GO:0071456 [cellular response to hypoxia]
GO:0075733 [intracellular transport of virus]
GO:0090090 [negative regulation of canonical Wnt signaling pathway]
GO:0090263 [positive regulation of canonical Wnt signaling pathway]
GO:0097190 [apoptotic signaling pathway]
GO:0097300 [programmed necrotic cell death]
GO:1901214 [regulation of neuron death]
GO:1902255 [positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator]
GO:1902527 [positive regulation of protein monoubiquitination]
Show all
 229 aa
25.8 kDa 		No 0
UBB-003
ENSP00000379180
ENST00000395839
P0CG47 [Direct mapping]
Polyubiquitin-B Ubiquitin
Q5U5U6 [Target identity:100%; Query identity:100%]
Ubiquitin B; Ubiquitin B, isoform CRA_a
Show all
Predicted intracellular proteins
Show all
GO:0000082 [G1/S transition of mitotic cell cycle]
GO:0000086 [G2/M transition of mitotic cell cycle]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0000187 [activation of MAPK activity]
GO:0000209 [protein polyubiquitination]
GO:0000278 [mitotic cell cycle]
GO:0000423 [macromitophagy]
GO:0000715 [nucleotide-excision repair, DNA damage recognition]
GO:0000724 [double-strand break repair via homologous recombination]
GO:0002223 [stimulatory C-type lectin receptor signaling pathway]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I]
GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005739 [mitochondrion]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005975 [carbohydrate metabolic process]
GO:0005978 [glycogen biosynthetic process]
GO:0006006 [glucose metabolic process]
GO:0006281 [DNA repair]
GO:0006283 [transcription-coupled nucleotide-excision repair]
GO:0006289 [nucleotide-excision repair]
GO:0006297 [nucleotide-excision repair, DNA gap filling]
GO:0006302 [double-strand break repair]
GO:0006351 [transcription, DNA-templated]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0006977 [DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest]
GO:0007166 [cell surface receptor signaling pathway]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007179 [transforming growth factor beta receptor signaling pathway]
GO:0007219 [Notch signaling pathway]
GO:0007220 [Notch receptor processing]
GO:0007249 [I-kappaB kinase/NF-kappaB signaling]
GO:0007254 [JNK cascade]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007411 [axon guidance]
GO:0007623 [circadian rhythm]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010008 [endosome membrane]
GO:0010467 [gene expression]
GO:0010803 [regulation of tumor necrosis factor-mediated signaling pathway]
GO:0010939 [regulation of necrotic cell death]
GO:0012501 [programmed cell death]
GO:0016032 [viral process]
GO:0016197 [endosomal transport]
GO:0016236 [macroautophagy]
GO:0019058 [viral life cycle]
GO:0019068 [virion assembly]
GO:0019082 [viral protein processing]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0019985 [translesion synthesis]
GO:0030512 [negative regulation of transforming growth factor beta receptor signaling pathway]
GO:0030666 [endocytic vesicle membrane]
GO:0031145 [anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process]
GO:0031398 [positive regulation of protein ubiquitination]
GO:0032479 [regulation of type I interferon production]
GO:0032480 [negative regulation of type I interferon production]
GO:0032481 [positive regulation of type I interferon production]
GO:0033209 [tumor necrosis factor-mediated signaling pathway]
GO:0033683 [nucleotide-excision repair, DNA incision]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0034220 [ion transmembrane transport]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0035872 [nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway]
GO:0036297 [interstrand cross-link repair]
GO:0038061 [NIK/NF-kappaB signaling]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042059 [negative regulation of epidermal growth factor receptor signaling pathway]
GO:0042276 [error-prone translesion synthesis]
GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I]
GO:0042769 [DNA damage response, detection of DNA damage]
GO:0042981 [regulation of apoptotic process]
GO:0043005 [neuron projection]
GO:0043025 [neuronal cell body]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043488 [regulation of mRNA stability]
GO:0044281 [small molecule metabolic process]
GO:0045087 [innate immune response]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0047497 [mitochondrion transport along microtubule]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048812 [neuron projection morphogenesis]
GO:0050852 [T cell receptor signaling pathway]
GO:0051092 [positive regulation of NF-kappaB transcription factor activity]
GO:0051403 [stress-activated MAPK cascade]
GO:0051436 [negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle]
GO:0051437 [positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition]
GO:0051439 [regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle]
GO:0051881 [regulation of mitochondrial membrane potential]
GO:0055085 [transmembrane transport]
GO:0061024 [membrane organization]
GO:0061136 [regulation of proteasomal protein catabolic process]
GO:0061418 [regulation of transcription from RNA polymerase II promoter in response to hypoxia]
GO:0070062 [extracellular exosome]
GO:0070266 [necroptotic process]
GO:0070423 [nucleotide-binding oligomerization domain containing signaling pathway]
GO:0070911 [global genome nucleotide-excision repair]
GO:0070987 [error-free translesion synthesis]
GO:0071456 [cellular response to hypoxia]
GO:0075733 [intracellular transport of virus]
GO:0090090 [negative regulation of canonical Wnt signaling pathway]
GO:0090263 [positive regulation of canonical Wnt signaling pathway]
GO:0097190 [apoptotic signaling pathway]
GO:0097300 [programmed necrotic cell death]
GO:1901214 [regulation of neuron death]
GO:1902255 [positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator]
GO:1902527 [positive regulation of protein monoubiquitination]
Show all
 229 aa
25.8 kDa 		No 0
UBB-005
ENSP00000437475
ENST00000535788
B4DV12 [Direct mapping]
Polyubiquitin-B; cDNA FLJ51326, highly similar to Homo sapiens ubiquitin B (UBB), mRNA
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
Show all
 153 aa
17.2 kDa 		No 0
UBB-006
ENSP00000464594
ENST00000577958
J3QSA3 [Direct mapping]
Polyubiquitin-B
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
Show all
 43 aa
4.9 kDa 		No 0
UBB-007
ENSP00000464510
ENST00000578706
J3QS39 [Direct mapping]
Polyubiquitin-B
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
Show all
 93 aa
10.5 kDa 		No 0
UBB-008
ENSP00000463156
ENST00000577640
J3QKN0 [Direct mapping]
Polyubiquitin-B
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
Show all
 206 aa
23.2 kDa 		No 0
UBB-201
ENSP00000478771
ENST00000614404
P0CG47 [Direct mapping]
Polyubiquitin-B Ubiquitin
Q5U5U6 [Target identity:100%; Query identity:100%]
Ubiquitin B; Ubiquitin B, isoform CRA_a
Show all
Predicted intracellular proteins
Show all
GO:0000082 [G1/S transition of mitotic cell cycle]
GO:0000086 [G2/M transition of mitotic cell cycle]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0000187 [activation of MAPK activity]
GO:0000209 [protein polyubiquitination]
GO:0000278 [mitotic cell cycle]
GO:0000423 [macromitophagy]
GO:0000715 [nucleotide-excision repair, DNA damage recognition]
GO:0000724 [double-strand break repair via homologous recombination]
GO:0002223 [stimulatory C-type lectin receptor signaling pathway]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I]
GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005739 [mitochondrion]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005975 [carbohydrate metabolic process]
GO:0005978 [glycogen biosynthetic process]
GO:0006006 [glucose metabolic process]
GO:0006281 [DNA repair]
GO:0006283 [transcription-coupled nucleotide-excision repair]
GO:0006289 [nucleotide-excision repair]
GO:0006297 [nucleotide-excision repair, DNA gap filling]
GO:0006302 [double-strand break repair]
GO:0006351 [transcription, DNA-templated]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0006977 [DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest]
GO:0007166 [cell surface receptor signaling pathway]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007179 [transforming growth factor beta receptor signaling pathway]
GO:0007219 [Notch signaling pathway]
GO:0007220 [Notch receptor processing]
GO:0007249 [I-kappaB kinase/NF-kappaB signaling]
GO:0007254 [JNK cascade]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007411 [axon guidance]
GO:0007623 [circadian rhythm]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010008 [endosome membrane]
GO:0010467 [gene expression]
GO:0010803 [regulation of tumor necrosis factor-mediated signaling pathway]
GO:0010939 [regulation of necrotic cell death]
GO:0012501 [programmed cell death]
GO:0016032 [viral process]
GO:0016197 [endosomal transport]
GO:0016236 [macroautophagy]
GO:0019058 [viral life cycle]
GO:0019068 [virion assembly]
GO:0019082 [viral protein processing]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0019985 [translesion synthesis]
GO:0030512 [negative regulation of transforming growth factor beta receptor signaling pathway]
GO:0030666 [endocytic vesicle membrane]
GO:0031145 [anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process]
GO:0031398 [positive regulation of protein ubiquitination]
GO:0032479 [regulation of type I interferon production]
GO:0032480 [negative regulation of type I interferon production]
GO:0032481 [positive regulation of type I interferon production]
GO:0033209 [tumor necrosis factor-mediated signaling pathway]
GO:0033683 [nucleotide-excision repair, DNA incision]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0034220 [ion transmembrane transport]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0035872 [nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway]
GO:0036297 [interstrand cross-link repair]
GO:0038061 [NIK/NF-kappaB signaling]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042059 [negative regulation of epidermal growth factor receptor signaling pathway]
GO:0042276 [error-prone translesion synthesis]
GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I]
GO:0042769 [DNA damage response, detection of DNA damage]
GO:0042981 [regulation of apoptotic process]
GO:0043005 [neuron projection]
GO:0043025 [neuronal cell body]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043488 [regulation of mRNA stability]
GO:0044281 [small molecule metabolic process]
GO:0045087 [innate immune response]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0047497 [mitochondrion transport along microtubule]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048812 [neuron projection morphogenesis]
GO:0050852 [T cell receptor signaling pathway]
GO:0051092 [positive regulation of NF-kappaB transcription factor activity]
GO:0051403 [stress-activated MAPK cascade]
GO:0051436 [negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle]
GO:0051437 [positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition]
GO:0051439 [regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle]
GO:0051881 [regulation of mitochondrial membrane potential]
GO:0055085 [transmembrane transport]
GO:0061024 [membrane organization]
GO:0061136 [regulation of proteasomal protein catabolic process]
GO:0061418 [regulation of transcription from RNA polymerase II promoter in response to hypoxia]
GO:0070062 [extracellular exosome]
GO:0070266 [necroptotic process]
GO:0070423 [nucleotide-binding oligomerization domain containing signaling pathway]
GO:0070911 [global genome nucleotide-excision repair]
GO:0070987 [error-free translesion synthesis]
GO:0071456 [cellular response to hypoxia]
GO:0075733 [intracellular transport of virus]
GO:0090090 [negative regulation of canonical Wnt signaling pathway]
GO:0090263 [positive regulation of canonical Wnt signaling pathway]
GO:0097190 [apoptotic signaling pathway]
GO:0097300 [programmed necrotic cell death]
GO:1901214 [regulation of neuron death]
GO:1902255 [positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator]
GO:1902527 [positive regulation of protein monoubiquitination]
Show all
 229 aa
25.8 kDa 		No 0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.