Expression of B3GNT2 in cancer - Summary

CANCER ATLAS

Gene description

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2

Protein class

Enzymes, Plasma proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA005997

GENE INFORMATION
Gene name	B3GNT2 (HGNC Symbol)
Synonyms	B3GN-T1, B3GN-T2, B3GNT-2, B3GNT1, BETA3GNT
Description	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains. [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband	p15
Chromosome location (bp)	62196113 - 62224731
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170340 (version 83.38)
Entrez gene	10678
UniProt	Q9NY97 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NY97
Antibodypedia	B3GNT2 antibodies

PROTEIN BROWSER

B3GNT2-001	B3GNT2-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
B3GNT2-001 ENSP00000305595 ENST00000301998	Q9NY97 [Direct mapping] N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006493 [protein O-linked glycosylation] GO:0007411 [axon guidance] GO:0007608 [sensory perception of smell] GO:0008378 [galactosyltransferase activity] GO:0008532 [N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0030203 [glycosaminoglycan metabolic process] GO:0030311 [poly-N-acetyllactosamine biosynthetic process] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0070062 [extracellular exosome] Show all	397 aa 46 kDa	No	1
B3GNT2-002 ENSP00000384692 ENST00000405767	Q9NY97 [Direct mapping] N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006493 [protein O-linked glycosylation] GO:0008378 [galactosyltransferase activity] GO:0008532 [N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0030203 [glycosaminoglycan metabolic process] GO:0030311 [poly-N-acetyllactosamine biosynthetic process] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0070062 [extracellular exosome] Show all	397 aa 46 kDa	No	1