Expression of TCAF2 in cancer - Summary

CANCER ATLAS

Gene description

TRPM8 channel-associated factor 2

Protein class

Enzymes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA038756	HPA038758

GENE INFORMATION
Gene name	TCAF2 (HGNC Symbol)
Synonyms	FAM115C, FAM139A, FLJ40722
Description	TRPM8 channel-associated factor 2 (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	q35
Chromosome location (bp)	143620950 - 143730409
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170379 (version 83.38)
Entrez gene	285966
UniProt	A6NFQ2 (UniProt - Evidence at protein level)
neXtProt	NX_A6NFQ2
Antibodypedia	TCAF2 antibodies

PROTEIN BROWSER

TCAF2-001	TCAF2-002	TCAF2-003	TCAF2-004	TCAF2-005	TCAF2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TCAF2-001 ENSP00000404265 ENST00000441159	A6NFQ2 [Direct mapping] TRPM8 channel-associated factor 2 Show all	Enzymes Peptidases Metallopeptidases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005886 [plasma membrane] GO:0006810 [transport] GO:0010360 [negative regulation of anion channel activity] GO:0030335 [positive regulation of cell migration] GO:0044325 [ion channel binding] GO:0090314 [positive regulation of protein targeting to membrane] Show all	919 aa 100.9 kDa	No	0
TCAF2-002 ENSP00000349902 ENST00000357344	A6NFQ2 [Direct mapping] TRPM8 channel-associated factor 2 Show all	Enzymes Peptidases Metallopeptidases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005886 [plasma membrane] GO:0006810 [transport] GO:0010360 [negative regulation of anion channel activity] GO:0030335 [positive regulation of cell migration] GO:0044325 [ion channel binding] GO:0090314 [positive regulation of protein targeting to membrane] Show all	845 aa 92 kDa	No	0
TCAF2-003 ENSP00000412724 ENST00000444908	A6NFQ2 [Direct mapping] TRPM8 channel-associated factor 2 Show all	Enzymes Peptidases Metallopeptidases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002244 [hematopoietic progenitor cell differentiation] GO:0005886 [plasma membrane] GO:0006810 [transport] GO:0010360 [negative regulation of anion channel activity] GO:0030335 [positive regulation of cell migration] GO:0044325 [ion channel binding] GO:0090314 [positive regulation of protein targeting to membrane] Show all	845 aa 92 kDa	No	0
TCAF2-004 ENSP00000389100 ENST00000411935	A6NFQ2 [Direct mapping] TRPM8 channel-associated factor 2 Show all	Enzymes Peptidases Metallopeptidases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005886 [plasma membrane] GO:0006810 [transport] GO:0010360 [negative regulation of anion channel activity] GO:0030335 [positive regulation of cell migration] GO:0044325 [ion channel binding] GO:0090314 [positive regulation of protein targeting to membrane] Show all	815 aa 90.6 kDa	No	0
TCAF2-005 ENSP00000431079 ENST00000518791	H0YC74 [Direct mapping] TRPM8 channel-associated factor 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		660 aa 72.2 kDa	No	0
TCAF2-201 ENSP00000441099 ENST00000425618	A6NFQ2 [Direct mapping] TRPM8 channel-associated factor 2 Show all	Enzymes Peptidases Metallopeptidases SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005886 [plasma membrane] GO:0006810 [transport] GO:0010360 [negative regulation of anion channel activity] GO:0030335 [positive regulation of cell migration] GO:0044325 [ion channel binding] GO:0090314 [positive regulation of protein targeting to membrane] Show all	815 aa 90.6 kDa	No	0