Expression of SLC30A1 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 30 (zinc transporter), member 1

Protein class

Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA015275

GENE INFORMATION
Gene name	SLC30A1 (HGNC Symbol)
Synonyms	ZNT1, ZRC1
Description	Solute carrier family 30 (zinc transporter), member 1 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q32.3
Chromosome location (bp)	211571568 - 211578742
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170385 (version 83.38)
Entrez gene	7779
UniProt	Q9Y6M5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y6M5
Antibodypedia	SLC30A1 antibodies

PROTEIN BROWSER

SLC30A1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC30A1-001 ENSP00000355968 ENST00000367001	Q9Y6M5 [Direct mapping] Zinc transporter 1 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001701 [in utero embryonic development] GO:0005385 [zinc ion transmembrane transporter activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0006812 [cation transport] GO:0006829 [zinc II ion transport] GO:0006874 [cellular calcium ion homeostasis] GO:0006882 [cellular zinc ion homeostasis] GO:0008324 [cation transmembrane transporter activity] GO:0010043 [response to zinc ion] GO:0016021 [integral component of membrane] GO:0019855 [calcium channel inhibitor activity] GO:0030315 [T-tubule] GO:0031965 [nuclear membrane] GO:0046929 [negative regulation of neurotransmitter secretion] GO:0055085 [transmembrane transport] GO:0061088 [regulation of sequestering of zinc ion] GO:0070509 [calcium ion import] GO:0070574 [cadmium ion transmembrane transport] GO:0071577 [zinc II ion transmembrane transport] GO:0071584 [negative regulation of zinc ion transmembrane import] GO:0071585 [detoxification of cadmium ion] GO:0090281 [negative regulation of calcium ion import] Show all	507 aa 55.3 kDa	No	6