Cell atlas - ZNF296 - The Human Protein Atlas

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ZNF296

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Centrosome
	Nucleoplasm

Human cell
	Centrosome
	Nucleoplasm

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GENERAL INFORMATION
Gene name	ZNF296
Gene description	Zinc finger protein 296
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm. In addition localized to the centrosome.
RNA cell category	Cell line enhanced (U-698)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)
Additional location	In addition localized to the Centrosome (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA049576
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (U-698) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm. In addition localized to the centrosome.

Main location

Nucleoplasm (approved)

Additional location

Centrosome (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA049576	HEK 293	Nucleoplasm
	HPA049576	HEK 293	Centrosome
	HPA049576	PC-3	Nucleoplasm
	HPA049576	U-2 OS	Nucleoplasm
	HPA049576	U-2 OS	Centrosome

GENE INFORMATION
Gene name	ZNF296 (HGNC Symbol)
Synonyms	ZNF342
Description	Zinc finger protein 296 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	q13.32
Chromosome location (bp)	45071500 - 45076588
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170684 (version 83.38)
Entrez gene	162979
UniProt	Q8WUU4 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8WUU4
Antibodypedia	ZNF296 antibodies

PROTEIN BROWSER

ZNF296-001	ZNF296-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF296-001 ENSP00000302770 ENST00000303809	Q8WUU4 [Direct mapping] Zinc finger protein 296 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001076 [transcription factor activity, RNA polymerase II transcription factor binding] GO:0003674 [molecular_function] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0007283 [spermatogenesis] GO:0046872 [metal ion binding] Show all	475 aa 50.8 kDa	No	0
ZNF296-201 ENSP00000479435 ENST00000622376	Q8IX33 [Direct mapping] Hepatocellular carcinoma-associated antigen HCA108; Zinc finger protein 296 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	451 aa 48.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.