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Cancer tissues showed moderate cytoplasmic staining. Few cases of lobular carcinomas of breast, stomach, colorectal, pancreas and endometrial cancers displayed strong positivity. Few cases of pancreatic cancers showed additional membranous staining.
Cancer tissues showed moderate to strong cytoplasmic staining. Few cases of cervix, ovary, pancreas and urothelial cancers displayed additional membranous positivity.
Moderate cytoplasmic staining was observed in most cancers. Several colorectal cancers were strongly stained. Renal, hepatocellular and testicular cancers were negative or weakly stained.
P33176 [Direct mapping] Kinesin-1 heavy chain V9HW29 [Target identity:100%; Query identity:100%] Kinesin-like protein
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Predicted intracellular proteins Plasma proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0003777 [microtubule motor activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005737 [cytoplasm] GO:0005815 [microtubule organizing center] GO:0005871 [kinesin complex] GO:0005874 [microtubule] GO:0007018 [microtubule-based movement] GO:0007028 [cytoplasm organization] GO:0007411 [axon guidance] GO:0008017 [microtubule binding] GO:0008104 [protein localization] GO:0008574 [ATP-dependent microtubule motor activity, plus-end-directed] GO:0016020 [membrane] GO:0030139 [endocytic vesicle] GO:0030705 [cytoskeleton-dependent intracellular transport] GO:0031982 [vesicle] GO:0032230 [positive regulation of synaptic transmission, GABAergic] GO:0035253 [ciliary rootlet] GO:0035617 [stress granule disassembly] GO:0042391 [regulation of membrane potential] GO:0043005 [neuron projection] GO:0043227 [membrane-bounded organelle] GO:0043268 [positive regulation of potassium ion transport] GO:0044267 [cellular protein metabolic process] GO:0047496 [vesicle transport along microtubule] GO:0048471 [perinuclear region of cytoplasm] GO:0072383 [plus-end-directed vesicle transport along microtubule] GO:0090004 [positive regulation of establishment of protein localization to plasma membrane]
