Expression of OR4D5 in cancer - Summary

CANCER ATLAS

Gene description

Olfactory receptor, family 4, subfamily D, member 5

Protein class

G-protein coupled receptors, Predicted membrane proteins

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA045005

GENE INFORMATION
Gene name	OR4D5
Synonyms
Description	Olfactory receptor, family 4, subfamily D, member 5 (HGNC Symbol)
Entrez gene summary	Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Chromosome	11
Cytoband	q24.1
Chromosome location (bp)	123939543 - 123940637
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000171014 (version 83.38)
Entrez gene	219875
UniProt	Q8NGN0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8NGN0
Antibodypedia	OR4D5 antibodies

PROTEIN BROWSER

OR4D5-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
OR4D5-001 ENSP00000305970 ENST00000307033	Q8NGN0 [Direct mapping] Olfactory receptor 4D5 Show all	G-protein coupled receptors Odorant/olfactory and gustatory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004888 [transmembrane signaling receptor activity] GO:0004930 [G-protein coupled receptor activity] GO:0004984 [olfactory receptor activity] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0050907 [detection of chemical stimulus involved in sensory perception] GO:0050911 [detection of chemical stimulus involved in sensory perception of smell] Show all	318 aa 35.8 kDa	No	7