Expression of FPR2 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Formyl peptide receptor 2

Protein class

G-protein coupled receptors, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA029154

GENE INFORMATION
Gene name	FPR2 (HGNC Symbol)
Synonyms	ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH2, FPRL1, HM63, LXA4R
Description	Formyl peptide receptor 2 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	q13.41
Chromosome location (bp)	51752026 - 51770526
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000171049 (version 83.38)
Entrez gene	2358
UniProt	P25090 (UniProt - Evidence at transcript level)
neXtProt	NX_P25090
Antibodypedia	FPR2 antibodies

PROTEIN BROWSER

FPR2-001	FPR2-002	FPR2-003	FPR2-005	FPR2-006	FPR2-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FPR2-001 ENSP00000340191 ENST00000340023	P25090 [Direct mapping] N-formyl peptide receptor 2 A0A024R4P3 [Target identity:100%; Query identity:100%] Formyl peptide receptor-like 1, isoform CRA_a Show all	G-protein coupled receptors GPCRs excl olfactory receptors Chemokines and chemotactic factors receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0004930 [G-protein coupled receptor activity] GO:0004982 [N-formyl peptide receptor activity] GO:0005886 [plasma membrane] GO:0006928 [movement of cell or subcellular component] GO:0006935 [chemotaxis] GO:0006954 [inflammatory response] GO:0007155 [cell adhesion] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	351 aa 39 kDa	No	7
FPR2-002 ENSP00000468876 ENST00000598953	P25090 [Direct mapping] N-formyl peptide receptor 2 A0A024R4P3 [Target identity:100%; Query identity:100%] Formyl peptide receptor-like 1, isoform CRA_a Show all	G-protein coupled receptors GPCRs excl olfactory receptors Chemokines and chemotactic factors receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0004982 [N-formyl peptide receptor activity] GO:0005886 [plasma membrane] GO:0006928 [movement of cell or subcellular component] GO:0006935 [chemotaxis] GO:0006954 [inflammatory response] GO:0007155 [cell adhesion] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	351 aa 39 kDa	No	7
FPR2-003 ENSP00000468897 ENST00000598776	P25090 [Direct mapping] N-formyl peptide receptor 2 A0A024R4P3 [Target identity:100%; Query identity:100%] Formyl peptide receptor-like 1, isoform CRA_a Show all	G-protein coupled receptors GPCRs excl olfactory receptors Chemokines and chemotactic factors receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0004930 [G-protein coupled receptor activity] GO:0004982 [N-formyl peptide receptor activity] GO:0005886 [plasma membrane] GO:0006928 [movement of cell or subcellular component] GO:0006935 [chemotaxis] GO:0006954 [inflammatory response] GO:0007155 [cell adhesion] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	351 aa 39 kDa	No	7
FPR2-005 ENSP00000472259 ENST00000600722	M0R222 [Direct mapping] N-formyl peptide receptor 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0004982 [N-formyl peptide receptor activity] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	124 aa 13.8 kDa	No	3
FPR2-006 ENSP00000470373 ENST00000600258	M0QZ89 [Direct mapping] N-formyl peptide receptor 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0004982 [N-formyl peptide receptor activity] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	88 aa 9.6 kDa	No	2
FPR2-007 ENSP00000469085 ENST00000599326	M0QXD3 [Direct mapping] N-formyl peptide receptor 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0004982 [N-formyl peptide receptor activity] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	137 aa 15.4 kDa	No	3