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MRPL36

CANCER ATLAS

Gene description

 Mitochondrial ribosomal protein L36

Protein class

 Predicted intracellular proteins, Ribosomal proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA047238

GENE INFORMATION

Gene name

 MRPL36 (HGNC Symbol)

Synonyms

 BRIP1, L36mt, MRP-L36, PRPL36, RPMJ

Description

 Mitochondrial ribosomal protein L36 (HGNC Symbol)

Entrez gene summary

 Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 2p. [provided by RefSeq, Jul 2008]

Chromosome

 5

Cytoband

 p15.33

Chromosome location (bp)

 1798386 - 1801366

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000171421 (version 83.38)

Entrez gene

 64979

UniProt

 Q9P0J6 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9P0J6

Antibodypedia

 MRPL36 antibodies

PROTEIN BROWSER
MRPL36-001
MRPL36-002
MRPL36-003
MRPL36-004
MRPL36-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MRPL36-001
ENSP00000423152
ENST00000505059
Q9P0J6 [Direct mapping]
39S ribosomal protein L36, mitochondrial
Show all
Ribosomal proteins
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005743 [mitochondrial inner membrane]
GO:0005762 [mitochondrial large ribosomal subunit]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0006996 [organelle organization]
GO:0032543 [mitochondrial translation]
GO:0042254 [ribosome biogenesis]
GO:0070124 [mitochondrial translational initiation]
GO:0070125 [mitochondrial translational elongation]
GO:0070126 [mitochondrial translational termination]
Show all
 103 aa
11.8 kDa 		No 0
MRPL36-002
ENSP00000423399
ENST00000508987
Q9P0J6 [Direct mapping]
39S ribosomal protein L36, mitochondrial
Show all
Ribosomal proteins
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005739 [mitochondrion]
GO:0005743 [mitochondrial inner membrane]
GO:0005762 [mitochondrial large ribosomal subunit]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0006996 [organelle organization]
GO:0032543 [mitochondrial translation]
GO:0042254 [ribosome biogenesis]
GO:0070124 [mitochondrial translational initiation]
GO:0070125 [mitochondrial translational elongation]
GO:0070126 [mitochondrial translational termination]
Show all
 103 aa
11.8 kDa 		No 0
MRPL36-003
ENSP00000372093
ENST00000382647
Q9P0J6 [Direct mapping]
39S ribosomal protein L36, mitochondrial
Show all
Ribosomal proteins
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005743 [mitochondrial inner membrane]
GO:0005762 [mitochondrial large ribosomal subunit]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0006996 [organelle organization]
GO:0032543 [mitochondrial translation]
GO:0042254 [ribosome biogenesis]
GO:0070124 [mitochondrial translational initiation]
GO:0070125 [mitochondrial translational elongation]
GO:0070126 [mitochondrial translational termination]
Show all
 103 aa
11.8 kDa 		No 0
MRPL36-004
ENSP00000424366
ENST00000510999
D6RB74 [Direct mapping]
39S ribosomal protein L36, mitochondrial
Show all
Predicted intracellular proteins
Show all
GO:0042254 [ribosome biogenesis]
Show all
 36 aa
4.1 kDa 		No 0
MRPL36-005
ENSP00000427152
ENST00000505818
Q9P0J6 [Direct mapping]
39S ribosomal protein L36, mitochondrial
Show all
Ribosomal proteins
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005743 [mitochondrial inner membrane]
GO:0005762 [mitochondrial large ribosomal subunit]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0006996 [organelle organization]
GO:0032543 [mitochondrial translation]
GO:0042254 [ribosome biogenesis]
GO:0070124 [mitochondrial translational initiation]
GO:0070125 [mitochondrial translational elongation]
GO:0070126 [mitochondrial translational termination]
Show all
 103 aa
11.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.