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KRT27

CANCER ATLAS

Gene description

 Keratin 27, type I

Protein class

 Plasma proteins, Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA055114

GENE INFORMATION

Gene name

 KRT27 (HGNC Symbol)

Synonyms

 KRT25C

Description

 Keratin 27, type I (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]

Chromosome

 17

Cytoband

 q21.2

Chromosome location (bp)

 40776808 - 40782534

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000171446 (version 83.38)

Entrez gene

 342574

UniProt

 Q7Z3Y8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q7Z3Y8

Antibodypedia

 KRT27 antibodies

PROTEIN BROWSER
KRT27-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
KRT27-001
ENSP00000301656
ENST00000301656
Q7Z3Y8 [Direct mapping]
Keratin, type I cytoskeletal 27
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005198 [structural molecule activity]
GO:0005737 [cytoplasm]
GO:0005882 [intermediate filament]
GO:0008150 [biological_process]
GO:0031069 [hair follicle morphogenesis]
GO:0070062 [extracellular exosome]
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 459 aa
49.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.