Expression of DLK2 in cancer - Summary - The Human Protein Atlas

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DLK2

TISSUE

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

Delta-like 2 homolog (Drosophila)

Protein class

Predicted membrane proteins

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA061223

GENE INFORMATION
Gene name	DLK2 (HGNC Symbol)
Synonyms	EGFL9, MGC2487
Description	Delta-like 2 homolog (Drosophila) (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	p21.1
Chromosome location (bp)	43450352 - 43456632
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000171462 (version 83.38)
Entrez gene	65989
UniProt	Q6UY11 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6UY11
Antibodypedia	DLK2 antibodies

PROTEIN BROWSER

DLK2-001	DLK2-002	DLK2-003	DLK2-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DLK2-001 ENSP00000361563 ENST00000372485	Q5T3T9 [Direct mapping] Protein delta homolog 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	377 aa 39.9 kDa	Yes	1
DLK2-002 ENSP00000399829 ENST00000430324	H0Y5P1 [Direct mapping] Protein delta homolog 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	289 aa 30.4 kDa	No	1
DLK2-003 ENSP00000349893 ENST00000357338	Q6UY11 [Direct mapping] Protein delta homolog 2 A0A024RD55 [Target identity:100%; Query identity:100%] EGF-like-domain, multiple 9, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0016021 [integral component of membrane] GO:0042803 [protein homodimerization activity] GO:0045598 [regulation of fat cell differentiation] GO:0045746 [negative regulation of Notch signaling pathway] GO:0070062 [extracellular exosome] Show all	383 aa 40.5 kDa	Yes	1
DLK2-005 ENSP00000361566 ENST00000372488	Q6UY11 [Direct mapping] Protein delta homolog 2 A0A024RD55 [Target identity:100%; Query identity:100%] EGF-like-domain, multiple 9, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0016021 [integral component of membrane] GO:0045746 [negative regulation of Notch signaling pathway] GO:0070062 [extracellular exosome] Show all	383 aa 40.5 kDa	Yes	1

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.