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MAP6

GENERAL INFORMATION

Gene name

 MAP6

Gene description

 Microtubule-associated protein 6

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (cerebral cortex, fallopian tube)
GTEx:Mixed
FANTOM5:Tissue enhanced (caudate, pituitary gland)

Protein evidence

 Evidence at protein level

Protein expression

 Selective cytoplasmic expression in CNS, peripheral nerve and renal glomeruli.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 4 antibodies.
HPA039061 , HPA039062 , CAB015442 , CAB022600
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Rectum

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (cerebral cortex, fallopian tube)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (caudate, pituitary gland)

GENE INFORMATION

Gene name

 MAP6 (HGNC Symbol)

Synonyms

 FLJ41346, KIAA1878, MAP6-N, STOP

Description

 Microtubule-associated protein 6 (HGNC Symbol)

Entrez gene summary

 This gene encodes a microtubule-associated protein. The encoded protein is a calmodulin-binding and calmodulin-regulated protein that is involved in microtubule stabilization. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Chromosome

 11

Cytoband

 q13.5

Chromosome location (bp)

 75586918 - 75669120

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000171533 (version 83.38)

Entrez gene

 4135

UniProt

 Q96JE9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96JE9

Antibodypedia

 MAP6 antibodies

PROTEIN BROWSER
MAP6-001
MAP6-002
MAP6-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MAP6-001
ENSP00000307093
ENST00000304771
Q96JE9 [Direct mapping]
Microtubule-associated protein 6
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000226 [microtubule cytoskeleton organization]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005794 [Golgi apparatus]
GO:0005874 [microtubule]
GO:0006810 [transport]
GO:0008017 [microtubule binding]
GO:0032418 [lysosome localization]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048813 [dendrite morphogenesis]
Show all
 813 aa
86.5 kDa 		No 0
MAP6-002
ENSP00000415108
ENST00000434603
Q96JE9 [Direct mapping]
Microtubule-associated protein 6
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000226 [microtubule cytoskeleton organization]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005794 [Golgi apparatus]
GO:0005874 [microtubule]
GO:0006810 [transport]
GO:0032418 [lysosome localization]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048813 [dendrite morphogenesis]
Show all
 439 aa
47.4 kDa 		No 0
MAP6-004
ENSP00000434278
ENST00000526740
Q96JE9 [Direct mapping]
Microtubule-associated protein 6
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000226 [microtubule cytoskeleton organization]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005794 [Golgi apparatus]
GO:0005874 [microtubule]
GO:0006810 [transport]
GO:0032418 [lysosome localization]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048813 [dendrite morphogenesis]
Show all
 484 aa
51.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.