Cell atlas - UTF1 - The Human Protein Atlas

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UTF1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	UTF1
Gene description	Undifferentiated embryonic cell transcription factor 1
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Group enriched (NTERA-2, RPMI-8226)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (NTERA-2, RPMI-8226) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	UTF1
Synonyms
Description	Undifferentiated embryonic cell transcription factor 1 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a leucine zipper-containing transcriptional coactivator that may link the upstream activator ATF2 with the basal transcription complex. The encoded protein is closely associated with chromatin and is required for the proper differentiation of embryonic carcinoma and embryonic stem cells. Found nearly exclusively in pluripotent cells, this protein can also serve as a transcriptional repressor. [provided by RefSeq, Nov 2015]
Chromosome	10
Cytoband	q26.3
Chromosome location (bp)	133230274 - 133231558
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000171794 (version 83.38)
Entrez gene	8433
UniProt	Q5T230 (UniProt - Evidence at protein level)
neXtProt	NX_Q5T230
Antibodypedia	UTF1 antibodies

PROTEIN BROWSER

UTF1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
UTF1-001 ENSP00000305906 ENST00000304477	Q5T230 [Direct mapping] Undifferentiated embryonic cell transcription factor 1 Show all	Predicted intracellular proteins Transcription factors Basic domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003713 [transcription coactivator activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0008584 [male gonad development] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0071837 [HMG box domain binding] Show all	341 aa 36.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.