Expression of LRRC15 in cancer - Summary

CANCER ATLAS

Gene description

Leucine rich repeat containing 15

Protein class

Plasma proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA035503

GENE INFORMATION
Gene name	LRRC15 (HGNC Symbol)
Synonyms	LIB
Description	Leucine rich repeat containing 15 (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	q29
Chromosome location (bp)	194355247 - 194369743
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000172061 (version 83.38)
Entrez gene	131578
UniProt	Q8TF66 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8TF66
Antibodypedia	LRRC15 antibodies

PROTEIN BROWSER

LRRC15-001	LRRC15-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LRRC15-001 ENSP00000306276 ENST00000347624	Q8TF66 [Direct mapping] Leucine-rich repeat-containing protein 15 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001968 [fibronectin binding] GO:0005515 [protein binding] GO:0005518 [collagen binding] GO:0016021 [integral component of membrane] GO:0030335 [positive regulation of cell migration] GO:0043236 [laminin binding] GO:0046813 [receptor-mediated virion attachment to host cell] GO:0070062 [extracellular exosome] GO:0090005 [negative regulation of establishment of protein localization to plasma membrane] Show all	581 aa 64.4 kDa	Yes	1
LRRC15-002 ENSP00000413707 ENST00000428839	Q8TF66 [Direct mapping] Leucine-rich repeat-containing protein 15 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001968 [fibronectin binding] GO:0005515 [protein binding] GO:0005518 [collagen binding] GO:0005622 [intracellular] GO:0016021 [integral component of membrane] GO:0030335 [positive regulation of cell migration] GO:0043236 [laminin binding] GO:0046813 [receptor-mediated virion attachment to host cell] GO:0070062 [extracellular exosome] GO:0090005 [negative regulation of establishment of protein localization to plasma membrane] Show all	587 aa 65 kDa	Yes	1