Tissue expression of INSL5 - Summary - The Human Protein Atlas

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INSL5

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TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	INSL5
Gene description	Insulin-like 5
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (rectum, colon)
GTEx:	Tissue enhanced (colon)

Protein evidence

Evidence at protein level

Protein expression

Selective cytoplasmic expression in a subset of neuroendocrine cells.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA030100 , CAB033849
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (rectum, colon)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (colon)

GENE INFORMATION
Gene name	INSL5
Synonyms
Description	Insulin-like 5 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene contains a classical signature of the insulin superfamily and is highly similar to relaxin 3 (RLN3/INSL7). [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	p31.3
Chromosome location (bp)	66797741 - 66801256
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000172410 (version 83.38)
Entrez gene	10022
UniProt	Q9Y5Q6 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y5Q6
Antibodypedia	INSL5 antibodies

PROTEIN BROWSER

INSL5-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
INSL5-001 ENSP00000302724 ENST00000304526	Q9Y5Q6 [Direct mapping] Insulin-like peptide INSL5 Insulin-like peptide INSL5 B chain Insulin-like peptide INSL5 A chain Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005179 [hormone activity] GO:0005575 [cellular_component] GO:0005576 [extracellular region] GO:0008150 [biological_process] GO:2000253 [positive regulation of feeding behavior] Show all	135 aa 15.3 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.