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INSL5

GENERAL INFORMATION

Gene name

 INSL5

Gene description

 Insulin-like 5

Protein class

 Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (rectum, colon)
GTEx:Tissue enhanced (colon)

Protein evidence

 Evidence at protein level

Protein expression

 Selective cytoplasmic expression in a subset of neuroendocrine cells.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA030100 , CAB033849
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical
Cerebral cortexHippocampusCaudateCerebellumThyroid glandParathyroid glandAdrenal glandAppendixBone marrowLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleNasopharynxBronchusLungLiverGallbladderPancreasOral mucosaSalivary glandEsophagusStomachDuodenumSmall intestineColonRectumKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastVaginaCervix, uterineEndometriumFallopian tubeOvaryPlacentaAdipose tissueSoft tissueSkinNotdetectedLowMediumHighSCORE

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (rectum, colon)
Cerebral cortexThyroid glandParathyroid glandAdrenal glandAppendixBone marrowLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleLungLiverGallbladderPancreasSalivary glandEsophagusStomachDuodenumSmall intestineColonRectumKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastCervix, uterineEndometriumFallopian tubeOvaryPlacentaAdipose tissueSkin020406080100120140TPM
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (colon)
HypothalamusPituitary glandCerebral cortexHippocampusCaudateCerebellumThyroid glandAdrenal glandSpleenHeart muscleSkeletal muscleLungLiverPancreasSalivary glandEsophagusStomachSmall intestineColonKidneyUrinary bladderTestisProstateBreastVaginaCervix, uterineEndometriumFallopian tubeOvaryAdipose tissueSkin0246810RPKM

GENE INFORMATION

Gene name

 INSL5

Synonyms

Description

 Insulin-like 5 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene contains a classical signature of the insulin superfamily and is highly similar to relaxin 3 (RLN3/INSL7). [provided by RefSeq, Jul 2008]

Chromosome

 1

Cytoband

 p31.3

Chromosome location (bp)

 66797741 - 66801256

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000172410 (version 83.38)

Entrez gene

 10022

UniProt

 Q9Y5Q6 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y5Q6

Antibodypedia

 INSL5 antibodies

PROTEIN BROWSER
INSL5-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
INSL5-001
ENSP00000302724
ENST00000304526
Q9Y5Q6 [Direct mapping]
Insulin-like peptide INSL5 Insulin-like peptide INSL5 B chain Insulin-like peptide INSL5 A chain
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   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
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GO:0005179 [hormone activity]
GO:0005575 [cellular_component]
GO:0005576 [extracellular region]
GO:0008150 [biological_process]
GO:2000253 [positive regulation of feeding behavior]
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 135 aa
15.3 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.