Expression of FIBP in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Fibroblast growth factor (acidic) intracellular binding protein

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA011729

GENE INFORMATION
Gene name	FIBP (HGNC Symbol)
Synonyms	FGFIBP
Description	Fibroblast growth factor (acidic) intracellular binding protein (HGNC Symbol)
Entrez gene summary	Acidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation. The FIBP protein is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF). It is postulated that FIBP may be involved in the mitogenic action of aFGF. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome	11
Cytoband	q13.1
Chromosome location (bp)	65883741 - 65888539
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000172500 (version 83.38)
Entrez gene	9158
UniProt	O43427 (UniProt - Evidence at protein level)
neXtProt	NX_O43427
Antibodypedia	FIBP antibodies

PROTEIN BROWSER

FIBP-001	FIBP-002	FIBP-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FIBP-001 ENSP00000344572 ENST00000338369	O43427 [Direct mapping] Acidic fibroblast growth factor intracellular-binding protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005739 [mitochondrion] GO:0008543 [fibroblast growth factor receptor signaling pathway] GO:0012505 [endomembrane system] GO:0016020 [membrane] GO:0017134 [fibroblast growth factor binding] GO:0070062 [extracellular exosome] GO:0070527 [platelet aggregation] Show all	364 aa 41.9 kDa	No	0
FIBP-002 ENSP00000350124 ENST00000357519	O43427 [Direct mapping] Acidic fibroblast growth factor intracellular-binding protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005739 [mitochondrion] GO:0008543 [fibroblast growth factor receptor signaling pathway] GO:0012505 [endomembrane system] GO:0016020 [membrane] GO:0017134 [fibroblast growth factor binding] GO:0070062 [extracellular exosome] GO:0070527 [platelet aggregation] Show all	357 aa 41.2 kDa	No	0
FIBP-007 ENSP00000434043 ENST00000533045	E9PSD3 [Direct mapping] Acidic fibroblast growth factor intracellular-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0017134 [fibroblast growth factor binding] Show all	348 aa 39.3 kDa	No	0