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SNTG2

GENERAL INFORMATION

Gene name

 SNTG2

Gene description

 Syntrophin, gamma 2

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (spleen, testis)
GTEx:Mixed
FANTOM5:Mixed

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (spleen, testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

 SNTG2 (HGNC Symbol)

Synonyms

 G2SYN, SYN5

Description

 Syntrophin, gamma 2 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described. [provided by RefSeq, Jul 2008]

Chromosome

 2

Cytoband

 p25.3

Chromosome location (bp)

 950868 - 1367613

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000172554 (version 83.38)

Entrez gene

 54221

UniProt

 Q9NY99 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NY99

Antibodypedia

 SNTG2 antibodies

PROTEIN BROWSER
SNTG2-001
SNTG2-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SNTG2-001
ENSP00000311837
ENST00000308624
Q9NY99 [Direct mapping]
Gamma-2-syntrophin
Show all
Predicted intracellular proteins
Show all
GO:0003779 [actin binding]
GO:0005198 [structural molecule activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0007417 [central nervous system development]
GO:0016013 [syntrophin complex]
GO:0030165 [PDZ domain binding]
GO:0042383 [sarcolemma]
GO:0097109 [neuroligin family protein binding]
Show all
 539 aa
60.2 kDa 		No 0
SNTG2-003
ENSP00000385020
ENST00000407292
Q9NY99 [Direct mapping]
Gamma-2-syntrophin
Show all
Predicted intracellular proteins
Show all
GO:0003779 [actin binding]
GO:0005198 [structural molecule activity]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0007417 [central nervous system development]
GO:0016013 [syntrophin complex]
GO:0030165 [PDZ domain binding]
GO:0042383 [sarcolemma]
GO:0097109 [neuroligin family protein binding]
Show all
 412 aa
46.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.