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Cancer cells generally showed moderate cytoplasmic positivity with a granular pattern. Most cases of endometrial cancer as well as several cases of colorectal and liver cancers were strongly stained. A majority of gliomas, lung and renal cancers were weakly stained or negative.
A majority of cancers exhibited moderate to strong cytoplasmic immunoreactivity, often with a granular pattern. Many cases of liver, renal and stomach cancers were weakly stained or negative.
GENE INFORMATION
Gene name
XKR3 (HGNC Symbol)
Synonyms
MGC57211, XTES
Description
XK, Kell blood group complex subunit-related family, member 3 (HGNC Symbol)
Entrez gene summary
XKRX (MIM 300684) and XKR3 are homologs of the Kell blood group precursor XK (MIM 314850), which is a putative membrane transporter and a component of the XK/Kell complex of the Kell blood group system (Calenda et al., 2006 [PubMed 16431037]).[supplied by OMIM, Mar 2008]
