Cell atlas - GXYLT2 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

GXYLT2

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS CELL CYCLE

GENE/PROTEIN

Antibody validation

Dictionary
	Cytokinetic bridge
	Midbody ring
	Nucleoplasm

Human cell
	Microtubules
	Nucleoplasm

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	GXYLT2
Gene description	Glucoside xylosyltransferase 2
Protein class	Enzymes Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm. In addition localized to the cytokinetic bridge & midbody ring.
RNA cell category	Cell line enhanced (MOLT-4)
Protein evidence	Evidence at transcript level
Main location	Localized to the Nucleoplasm (approved)
Additional location	In addition localized to the Cytokinetic bridge (approved), Midbody ring (approved)
Single-cell variation	Single-cell variation in protein expression observed.
Cell cycle dependency	Cell cycle dependent expression determined by biological definition

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA068429
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (MOLT-4) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm. In addition localized to the cytokinetic bridge & midbody ring.

Main location

Nucleoplasm (approved)

Additional location

Cytokinetic bridge (approved), Midbody ring (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA068429	Hep G2	Nucleoplasm
	HPA068429	SiHa	Nucleoplasm
			Cytokinetic bridge	Intensity	Intensity
			Midbody ring	Intensity	Intensity
	HPA068429	U-2 OS	Nucleoplasm

CELL CYCLE
Summary	Expression has cell cycle dependency according to biological definition
Intensity variation	Cytokinetic bridge

GENE INFORMATION
Gene name	GXYLT2 (HGNC Symbol)
Synonyms	GLT8D4
Description	Glucoside xylosyltransferase 2 (HGNC Symbol)
Entrez gene summary	GXYLT2 is a xylosyltransferase (EC 2.4.2.-) that adds the first xylose to O-glucose-modified residues in the epidermal growth factor (EGF; MIM 131530) repeats of proteins such as NOTCH1 (MIM 190198) (Sethi et al., 2010 [PubMed 19940119]).[supplied by OMIM, Mar 2010]
Chromosome	3
Cytoband	p13
Chromosome location (bp)	72888073 - 72998138
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000172986 (version 83.38)
Entrez gene	727936
UniProt	A0PJZ3 (UniProt - Evidence at transcript level)
neXtProt	NX_A0PJZ3
Antibodypedia	GXYLT2 antibodies

PROTEIN BROWSER

GXYLT2-001	GXYLT2-002	GXYLT2-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GXYLT2-001 ENSP00000374268 ENST00000389617	A0PJZ3 [Direct mapping] Glucoside xylosyltransferase 2 Show all	Enzymes ENZYME proteins Transferases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0016021 [integral component of membrane] GO:0016266 [O-glycan processing] GO:0016757 [transferase activity, transferring glycosyl groups] GO:0035252 [UDP-xylosyltransferase activity] Show all	443 aa 51.1 kDa	Yes	0
GXYLT2-002 ENSP00000417239 ENST00000498315	C9J3Q6 [Direct mapping] Glucoside xylosyltransferase 2 Show all	Predicted intracellular proteins Show all		102 aa 12.3 kDa	No	0
GXYLT2-003 ENSP00000420426 ENST00000491839	C9JND4 [Direct mapping] Glucoside xylosyltransferase 2 Show all	Predicted intracellular proteins Show all	GO:0016757 [transferase activity, transferring glycosyl groups] Show all	164 aa 19.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.