Tissue expression of RXFP4 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	RXFP4
Gene description	Relaxin/insulin-like family peptide receptor 4
Protein class	G-protein coupled receptors Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (rectum, colon, duodenum)
GTEx:	Tissue enhanced (colon, small intestine)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (rectum, colon, duodenum)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (colon, small intestine)

GENE INFORMATION
Gene name	RXFP4 (HGNC Symbol)
Synonyms	GPCR142, GPR100, RLN3R2, RXFPR4
Description	Relaxin/insulin-like family peptide receptor 4 (HGNC Symbol)
Entrez gene summary	GPR100 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).[supplied by OMIM, Mar 2008]
Chromosome	1
Cytoband	q22
Chromosome location (bp)	155941710 - 155942949
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000173080 (version 83.38)
Entrez gene	339403
UniProt	Q8TDU9 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TDU9
Antibodypedia	RXFP4 antibodies

PROTEIN BROWSER

RXFP4-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RXFP4-001 ENSP00000357301 ENST00000368318	Q8TDU9 [Direct mapping] Relaxin-3 receptor 2 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0004945 [angiotensin type II receptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007218 [neuropeptide signaling pathway] GO:0008528 [G-protein coupled peptide receptor activity] GO:0016021 [integral component of membrane] GO:0038166 [angiotensin-activated signaling pathway] GO:2000253 [positive regulation of feeding behavior] Show all	374 aa 41.1 kDa	No	7