Expression of ACSM6 in cancer - Summary

CANCER ATLAS

Gene description

Acyl-CoA synthetase medium-chain family member 6

Protein class

Enzymes, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA044593

GENE INFORMATION
Gene name	ACSM6 (HGNC Symbol)
Synonyms	bA310E22.3, C10orf129
Description	Acyl-CoA synthetase medium-chain family member 6 (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband	q23.33
Chromosome location (bp)	95194200 - 95228928
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000173124 (version 83.38)
Entrez gene	142827
UniProt	Q6P461 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6P461
Antibodypedia	ACSM6 antibodies

PROTEIN BROWSER

ACSM6-001	ACSM6-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ACSM6-001 ENSP00000377573 ENST00000394005	Q6P461 [Direct mapping] Acyl-coenzyme A synthetase ACSM6, mitochondrial Show all	Enzymes ENZYME proteins Ligase Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0003824 [catalytic activity] GO:0005524 [ATP binding] GO:0005525 [GTP binding] GO:0005739 [mitochondrion] GO:0006631 [fatty acid metabolic process] GO:0008152 [metabolic process] GO:0031647 [regulation of protein stability] GO:0046872 [metal ion binding] GO:0047760 [butyrate-CoA ligase activity] GO:1903955 [positive regulation of protein targeting to mitochondrion] Show all	480 aa 53.6 kDa	No	2
ACSM6-201 ENSP00000340296 ENST00000341686	Q6P461 [Direct mapping] Acyl-coenzyme A synthetase ACSM6, mitochondrial Show all	Enzymes ENZYME proteins Ligase Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0003824 [catalytic activity] GO:0005524 [ATP binding] GO:0005525 [GTP binding] GO:0005739 [mitochondrion] GO:0006631 [fatty acid metabolic process] GO:0008152 [metabolic process] GO:0031647 [regulation of protein stability] GO:0046872 [metal ion binding] GO:0047760 [butyrate-CoA ligase activity] GO:1903955 [positive regulation of protein targeting to mitochondrion] Show all	480 aa 53.6 kDa	No	2