Tissue expression of ZBTB21 - Summary - The Human Protein Atlas

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ZBTB21

TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ZBTB21
Gene description	Zinc finger and BTB domain containing 21
Protein class	Plasma proteins Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Nuclear expression in several tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA024655
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	ZBTB21 (HGNC Symbol)
Synonyms	KIAA1227, ZNF295
Description	Zinc finger and BTB domain containing 21 (HGNC Symbol)
Entrez gene summary
Chromosome	21
Cytoband	q22.3
Chromosome location (bp)	41986831 - 42010387
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000173276 (version 83.38)
Entrez gene	49854
UniProt	Q9ULJ3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9ULJ3
Antibodypedia	ZBTB21 antibodies

PROTEIN BROWSER

ZBTB21-001	ZBTB21-002	ZBTB21-003	ZBTB21-004	ZBTB21-005	ZBTB21-006	ZBTB21-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZBTB21-001 ENSP00000381512 ENST00000398499	Q9ULJ3 [Direct mapping] Zinc finger and BTB domain-containing protein 21 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0008327 [methyl-CpG binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	1066 aa 118.9 kDa	No	0
ZBTB21-002 ENSP00000381523 ENST00000398511	Q9ULJ3 [Direct mapping] Zinc finger and BTB domain-containing protein 21 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0008327 [methyl-CpG binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	1066 aa 118.9 kDa	No	0
ZBTB21-003 ENSP00000395186 ENST00000449949	Q5KS07 [Direct mapping] Zinc finger and BTB domain-containing protein 21; Zinc finger protein 295 variant 1; Zinc finger protein 295 variant 3; Zinc finger protein 295 variant 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	49 aa 5.5 kDa	No	0
ZBTB21-004 ENSP00000381517 ENST00000398505	Q9ULJ3 [Direct mapping] Zinc finger and BTB domain-containing protein 21 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0008327 [methyl-CpG binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	865 aa 95.8 kDa	No	0
ZBTB21-005 ENSP00000308759 ENST00000310826	Q9ULJ3 [Direct mapping] Zinc finger and BTB domain-containing protein 21 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0008327 [methyl-CpG binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	1066 aa 118.9 kDa	No	0
ZBTB21-006 ENSP00000381510 ENST00000398497	Q5KS07 [Direct mapping] Zinc finger and BTB domain-containing protein 21; Zinc finger protein 295 variant 1; Zinc finger protein 295 variant 3; Zinc finger protein 295 variant 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	49 aa 5.5 kDa	No	0
ZBTB21-008 ENSP00000387788 ENST00000425521	E7EVF9 [Direct mapping] Zinc finger and BTB domain-containing protein 21 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	119 aa 13.3 kDa	No	0

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The Human Protein Atlas

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