Cell atlas - NAA20 - The Human Protein Atlas

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NAA20

TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol

Human cell
	Cytosol

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GENERAL INFORMATION
Gene name	NAA20
Gene description	N(alpha)-acetyltransferase 20, NatB catalytic subunit
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA063344
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol.

Main location

Cytosol (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA063344	PC-3	Cytosol
	HPA063344	RH-30	Cytosol
	HPA063344	U-2 OS	Cytosol

GENE INFORMATION
Gene name	NAA20 (HGNC Symbol)
Synonyms	dJ1002M8.1, NAT3, NAT5
Description	N(alpha)-acetyltransferase 20, NatB catalytic subunit (HGNC Symbol)
Entrez gene summary	NAT5 is a component of N-acetyltransferase complex B (NatB). Human NatB performs cotranslational N(alpha)-terminal acetylation of methionine residues when they are followed by asparagine (Starheim et al., 2008 [PubMed 18570629]).[supplied by OMIM, Apr 2009]
Chromosome	20
Cytoband	p11.23
Chromosome location (bp)	20017116 - 20033655
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000173418 (version 83.38)
Entrez gene	51126
UniProt	P61599 (UniProt - Evidence at protein level)
neXtProt	NX_P61599
Antibodypedia	NAA20 antibodies

PROTEIN BROWSER

NAA20-001	NAA20-006	NAA20-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NAA20-001 ENSP00000335636 ENST00000334982	P61599 [Direct mapping] N-alpha-acetyltransferase 20 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004596 [peptide alpha-N-acetyltransferase activity] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0008080 [N-acetyltransferase activity] GO:0017196 [N-terminal peptidyl-methionine acetylation] GO:0031416 [NatB complex] Show all	178 aa 20.4 kDa	No	0
NAA20-006 ENSP00000311027 ENST00000310450	P61599 [Direct mapping] N-alpha-acetyltransferase 20 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004596 [peptide alpha-N-acetyltransferase activity] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0008080 [N-acetyltransferase activity] GO:0017196 [N-terminal peptidyl-methionine acetylation] GO:0031416 [NatB complex] Show all	111 aa 12.7 kDa	No	0
NAA20-007 ENSP00000381603 ENST00000398602	A8MZB2 [Direct mapping] N-acetyltransferase 5 (ARD1 homolog, S. cerevisiae), isoform CRA_a; N-alpha-acetyltransferase 20 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004596 [peptide alpha-N-acetyltransferase activity] GO:0005737 [cytoplasm] GO:0008080 [N-acetyltransferase activity] GO:0017196 [N-terminal peptidyl-methionine acetylation] GO:0031416 [NatB complex] Show all	166 aa 18.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.