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MOB1B

GENERAL INFORMATION

Gene name

 MOB1B

Gene description

 MOB kinase activator 1B

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene.

Reliability score

 Supported based on 1 antibody.
HPA047088
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Adrenal gland

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 MOB1B (HGNC Symbol)

Synonyms

 MOB4A, MOBKL1A

Description

 MOB kinase activator 1B (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Chromosome

 4

Cytoband

 q13.3

Chromosome location (bp)

 70902326 - 71022449

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000173542 (version 83.38)

Entrez gene

 92597

UniProt

 Q7L9L4 (UniProt - Evidence at protein level)

neXtProt

 NX_Q7L9L4

Antibodypedia

 MOB1B antibodies

PROTEIN BROWSER
MOB1B-001
MOB1B-002
MOB1B-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MOB1B-001
ENSP00000310189
ENST00000309395
Q7L9L4 [Direct mapping]
MOB kinase activator 1B
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0019209 [kinase activator activity]
GO:0019900 [kinase binding]
GO:0035329 [hippo signaling]
GO:0042327 [positive regulation of phosphorylation]
GO:0046777 [protein autophosphorylation]
GO:0046872 [metal ion binding]
GO:0070062 [extracellular exosome]
Show all
 216 aa
25.1 kDa 		No 0
MOB1B-002
ENSP00000379366
ENST00000396051
Q7L9L4 [Direct mapping]
MOB kinase activator 1B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0019209 [kinase activator activity]
GO:0019900 [kinase binding]
GO:0035329 [hippo signaling]
GO:0042327 [positive regulation of phosphorylation]
GO:0046777 [protein autophosphorylation]
GO:0046872 [metal ion binding]
GO:0070062 [extracellular exosome]
Show all
 221 aa
25.5 kDa 		No 0
MOB1B-004
ENSP00000427216
ENST00000502869
D6RCK3 [Direct mapping]
MOB kinase activator 1B
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 130 aa
14.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.