Tissue expression of APOBEC4 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	APOBEC4
Gene description	Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (fallopian tube, testis)
GTEx:	Tissue enriched (testis)
FANTOM5:	Tissue enriched (testis)

Protein evidence

Evidence at transcript level

Protein expression

Cytoplasmic expression in a few tissues. Distinct expression in internal elastic lamina of some vessels.

DATA RELIABILITY
Data reliability description	Pending external verification. Presumed off target binding observed and disregarded.
Reliability score	Approved based on 2 antibodies. HPA015636 , HPA015637
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (fallopian tube, testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	APOBEC4 (HGNC Symbol)
Synonyms	C1orf169, FLJ25691, MGC26594, RP1-127C7.4
Description	Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases, which convert cytidine to uridine. Other AID/APOBEC family members are involved in mRNA editing, somatic hypermutation and recombination of immunoglobulin genes, and innate immunity to retroviral infection. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	q25.3
Chromosome location (bp)	183646404 - 183653316
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000173627 (version 83.38)
Entrez gene	403314
UniProt	Q8WW27 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8WW27
Antibodypedia	APOBEC4 antibodies

PROTEIN BROWSER

APOBEC4-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
APOBEC4-001 ENSP00000310622 ENST00000308641	Q8WW27 [Direct mapping] Putative C->U-editing enzyme APOBEC-4 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0006397 [mRNA processing] GO:0008270 [zinc ion binding] GO:0016814 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines] Show all	367 aa 41.6 kDa	No	0