Cell atlas - GOLIM4 - The Human Protein Atlas

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GOLIM4

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TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS CUSTOM DATA

GENE/PROTEIN

Antibody validation

Dictionary
	Golgi apparatus

Human cell
	Golgi Apparatus

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GENERAL INFORMATION
Gene name	GOLIM4
Gene description	Golgi integral membrane protein 4
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the Golgi apparatus.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Golgi apparatus (validated)

DATA RELIABILITY
Reliability score	Validated based on 1 antibody. HPA001677
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the Golgi apparatus.

Main location

Golgi apparatus (validated)


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Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA001677	A-431	Golgi apparatus
	HPA001677	U-2 OS	Golgi apparatus
	HPA001677	U-251 MG	Golgi apparatus

CUSTOM DATA


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Thumbnail	Antibody	Cell line	Assay	Description
	HPA001677	U-2 OS	Image	Co-localization with the cis-Golgi marker GM130/GOLGA2 (RRID:AB_398141) for a refined protein localization within the Golgi apparatus in U-2 OS cells. GOLIM4 localizes to the Golgi apparatus, but not to the cis-Golgi compartment.

GENE INFORMATION
Gene name	GOLIM4 (HGNC Symbol)
Synonyms	GIMPC, GOLPH4, GPP130, P138
Description	Golgi integral membrane protein 4 (HGNC Symbol)
Entrez gene summary	The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi-resident protein. It may process proteins synthesized in the rough endoplasmic reticulum and assist in the transport of protein cargo through the Golgi apparatus. [provided by RefSeq, Jul 2008]
Chromosome	3
Cytoband	q26.2
Chromosome location (bp)	168008677 - 168095975
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000173905 (version 83.38)
Entrez gene	27333
UniProt	O00461 (UniProt - Evidence at protein level)
neXtProt	NX_O00461
Antibodypedia	GOLIM4 antibodies

PROTEIN BROWSER

GOLIM4-001	GOLIM4-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GOLIM4-001 ENSP00000417354 ENST00000470487	O00461 [Direct mapping] Golgi integral membrane protein 4 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0005794 [Golgi apparatus] GO:0005796 [Golgi lumen] GO:0005801 [cis-Golgi network] GO:0006810 [transport] GO:0010008 [endosome membrane] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030139 [endocytic vesicle] GO:0032580 [Golgi cisterna membrane] Show all	696 aa 81.9 kDa	No	1
GOLIM4-002 ENSP00000309893 ENST00000309027	F8W785 [Direct mapping] Golgi integral membrane protein 4 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005794 [Golgi apparatus] GO:0016021 [integral component of membrane] Show all	668 aa 78.8 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.