Expression of EVX2 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Even-skipped homeobox 2

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA041576

GENE INFORMATION
Gene name	EVX2
Synonyms
Description	Even-skipped homeobox 2 (HGNC Symbol)
Entrez gene summary	This gene is located at the 5' end of the HOXD gene cluster on chromosome 2. The encoded protein is a homeobox transcription factor that is related to the protein encoded by the Drosophila even-skipped (eve) gene, a member of the pair-rule class of segmentation genes. A 117 kb microdeletion at the 5' end of the HOXD gene cluster, which includes this gene and the HOXD9-HOXD13 genes, causes synpolydactyly, a dominantly inherited disease resulting in limb malformation. [provided by RefSeq, Sep 2009]
Chromosome	2
Cytoband	q31.1
Chromosome location (bp)	176077472 - 176083913
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000174279 (version 83.38)
Entrez gene	344191
UniProt	Q03828 (UniProt - Evidence at transcript level)
neXtProt	NX_Q03828
Antibodypedia	EVX2 antibodies

PROTEIN BROWSER

EVX2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EVX2-001 ENSP00000312385 ENST00000308618	Q03828 [Direct mapping] Homeobox even-skipped homolog protein 2 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Show all	GO:0003677 [DNA binding] GO:0005654 [nucleoplasm] GO:0006355 [regulation of transcription, DNA-templated] GO:0008150 [biological_process] GO:0035108 [limb morphogenesis] GO:0043565 [sequence-specific DNA binding] Show all	476 aa 47.8 kDa	No	0