Cell atlas - DIRC1 - The Human Protein Atlas

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DIRC1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol

Human cell
	Cytosol

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GENERAL INFORMATION
Gene name	DIRC1
Gene description	Disrupted in renal carcinoma 1
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol.
RNA cell category	Cell line enriched (ASC TERT1)
Protein evidence	Evidence at transcript level
Main location	Localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA056566
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (ASC TERT1) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol.

Main location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA056566	ASC TERT1	Cytosol
	HPA056566	U-2 OS	No staining

GENE INFORMATION
Gene name	DIRC1
Synonyms
Description	Disrupted in renal carcinoma 1 (HGNC Symbol)
Entrez gene summary	This gene consists of two exons and encodes a 104aa protein. Disruption of this gene by translocation t(2;3)(q33;q21) is associated with familial clear cell renal cancer. [provided by RefSeq, Sep 2010]
Chromosome	2
Cytoband	q32.2
Chromosome location (bp)	188734155 - 188790104
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000174325 (version 83.38)
Entrez gene	116093
UniProt	Q969H9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q969H9
Antibodypedia	DIRC1 antibodies

PROTEIN BROWSER

DIRC1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DIRC1-001 ENSP00000307860 ENST00000308100	Q969H9 [Direct mapping] Disrupted in renal carcinoma protein 1 Show all	Predicted intracellular proteins Disease related genes Show all		104 aa 11.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.