Expression of GLIS1 in cancer - Summary

CANCER ATLAS

Gene description

GLIS family zinc finger 1

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA001409

GENE INFORMATION
Gene name	GLIS1 (HGNC Symbol)
Synonyms	FLJ36155
Description	GLIS family zinc finger 1 (HGNC Symbol)
Entrez gene summary	GLIS1 is a GLI (MIM 165220)-related Kruppel-like zinc finger protein that functions as an activator and repressor of transcription (Kim et al., 2002 [PubMed 12042312]).[supplied by OMIM, Mar 2008]
Chromosome	1
Cytoband	p32.3
Chromosome location (bp)	53506237 - 53738106
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000174332 (version 83.38)
Entrez gene	148979
UniProt	Q8NBF1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8NBF1
Antibodypedia	GLIS1 antibodies

PROTEIN BROWSER

GLIS1-001	GLIS1-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GLIS1-001 ENSP00000309653 ENST00000312233	Q8NBF1 [Direct mapping] Zinc finger protein GLIS1 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0001227 [transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0001228 [transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006366 [transcription from RNA polymerase II promoter] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] Show all	620 aa 66 kDa	No	0
GLIS1-002 ENSP00000486112 ENST00000628545	A0A0D9SEX9 [Direct mapping] Zinc finger protein GLIS1 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	795 aa 84.4 kDa	No	0