Cell atlas - RALGAPA1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

RALGAPA1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Mitochondria

Human cell
	Cytosol
	Mitochondria

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	RALGAPA1
Gene description	Ral GTPase activating protein, alpha subunit 1 (catalytic)
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	6
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the cytosol. In addition localized to the mitochondria.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (approved)
Additional location	In addition localized to the Mitochondria (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA000851
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the cytosol. In addition localized to the mitochondria.

Main location

Cytosol (approved)

Additional location

Mitochondria (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA000851	A-431	Cytosol
	HPA000851	U-2 OS	Mitochondria
	HPA000851	U-2 OS	Cytosol
	HPA000851	U-251 MG	Cytosol

GENE INFORMATION
Gene name	RALGAPA1 (HGNC Symbol)
Synonyms	DKFZp667F074, GARNL1, GRIPE, KIAA0884, RalGAPalpha1, Tulip1
Description	Ral GTPase activating protein, alpha subunit 1 (catalytic) (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q13.2
Chromosome location (bp)	35538352 - 35809304
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000174373 (version 83.38)
Entrez gene	253959
UniProt	Q6GYQ0 (UniProt - Evidence at protein level)
neXtProt	NX_Q6GYQ0
Antibodypedia	RALGAPA1 antibodies

PROTEIN BROWSER

RALGAPA1-001	RALGAPA1-002	RALGAPA1-003	RALGAPA1-006	RALGAPA1-007	RALGAPA1-019

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RALGAPA1-001 ENSP00000302647 ENST00000307138	Q6GYQ0 [Direct mapping] Ral GTPase-activating protein subunit alpha-1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005488 [binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006355 [regulation of transcription, DNA-templated] GO:0046982 [protein heterodimerization activity] GO:0051056 [regulation of small GTPase mediated signal transduction] GO:0090630 [activation of GTPase activity] Show all	2083 aa 234.7 kDa	No	2
RALGAPA1-002 ENSP00000374348 ENST00000389698	Q6GYQ0 [Direct mapping] Ral GTPase-activating protein subunit alpha-1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005488 [binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0046982 [protein heterodimerization activity] GO:0051056 [regulation of small GTPase mediated signal transduction] GO:0090630 [activation of GTPase activity] Show all	2036 aa 229.8 kDa	No	2
RALGAPA1-003 ENSP00000371803 ENST00000382366	Q6GYQ0 [Direct mapping] Ral GTPase-activating protein subunit alpha-1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005488 [binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0046982 [protein heterodimerization activity] GO:0051056 [regulation of small GTPase mediated signal transduction] GO:0090630 [activation of GTPase activity] Show all	2049 aa 231.1 kDa	No	2
RALGAPA1-006 ENSP00000450574 ENST00000554573	H0YJ04 [Direct mapping] Ral GTPase-activating protein subunit alpha-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005737 [cytoplasm] GO:0051056 [regulation of small GTPase mediated signal transduction] GO:0090630 [activation of GTPase activity] Show all	356 aa 40.9 kDa	No	0
RALGAPA1-007 ENSP00000451877 ENST00000553892	Q6GYQ0 [Direct mapping] Ral GTPase-activating protein subunit alpha-1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005488 [binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0046982 [protein heterodimerization activity] GO:0051056 [regulation of small GTPase mediated signal transduction] GO:0090630 [activation of GTPase activity] Show all	2083 aa 234.9 kDa	No	2
RALGAPA1-019 ENSP00000451133 ENST00000554259	H0YJB5 [Direct mapping] Ral GTPase-activating protein subunit alpha-1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005737 [cytoplasm] GO:0051056 [regulation of small GTPase mediated signal transduction] GO:0090630 [activation of GTPase activity] Show all	722 aa 81 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.