Tissue expression of STARD6 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	STARD6
Gene description	StAR-related lipid transfer (START) domain containing 6
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (testis)
GTEx:	Tissue enriched (testis)
FANTOM5:	Tissue enriched (testis)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	STARD6
Synonyms
Description	StAR-related lipid transfer (START) domain containing 6 (HGNC Symbol)
Entrez gene summary	Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD6 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM, Mar 2008]
Chromosome	18
Cytoband	q21.2
Chromosome location (bp)	54324358 - 54357964
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000174448 (version 83.38)
Entrez gene	147323
UniProt	P59095 (UniProt - Evidence at protein level)
neXtProt	NX_P59095
Antibodypedia	STARD6 antibodies

PROTEIN BROWSER

STARD6-001	STARD6-003	STARD6-004	STARD6-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
STARD6-001 ENSP00000462349 ENST00000581310	P59095 [Direct mapping] StAR-related lipid transfer protein 6 Show all	Predicted intracellular proteins Show all	GO:0006869 [lipid transport] GO:0008289 [lipid binding] Show all	220 aa 25 kDa	No	0
STARD6-003 ENSP00000464406 ENST00000577499	J3QRT9 [Direct mapping] START domain containing 6, isoform CRA_b; StAR-related lipid transfer protein 6 Show all	Predicted intracellular proteins Show all		75 aa 8.3 kDa	No	0
STARD6-004 ENSP00000464377 ENST00000584040	J3QRT9 [Direct mapping] START domain containing 6, isoform CRA_b; StAR-related lipid transfer protein 6 Show all	Predicted intracellular proteins Show all		75 aa 8.3 kDa	No	0
STARD6-201 ENSP00000310814 ENST00000307844	P59095 [Direct mapping] StAR-related lipid transfer protein 6 Show all	Predicted intracellular proteins Show all	GO:0006869 [lipid transport] GO:0008289 [lipid binding] Show all	220 aa 25 kDa	No	0