Fields »
ABOUT
HELP
BLOG
SLC26A9

GENERAL INFORMATION

Gene name

 SLC26A9

Gene description

 Solute carrier family 26 (anion exchanger), member 9

Protein class

 Predicted membrane proteins
Transporters

Predicted localization

 Membrane

Number of transcripts

 3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (salivary gland, stomach)
GTEx:Tissue enhanced (stomach)
FANTOM5:Tissue enriched (salivary gland)

Protein evidence

 Evidence at protein level

Protein expression

 Luminal membranous and cytoplasmic expression in salivary and stomach glandular cells.

DATA RELIABILITY

Data reliability
description

 Presumed off target binding observed and disregarded. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA051485
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Stomach

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (salivary gland, stomach)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (stomach)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (salivary gland)

GENE INFORMATION

Gene name

 SLC26A9

Synonyms

Description

 Solute carrier family 26 (anion exchanger), member 9 (HGNC Symbol)

Entrez gene summary

 This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures yet have markedly different tissue expression patterns. The product of this gene is a highly selective chloride ion channel regulated by WNK kinases. Alternative splicing results in multiple transcript variants encoding differing isoforms.[provided by RefSeq, Dec 2008]

Chromosome

 1

Cytoband

 q32.1

Chromosome location (bp)

 205913048 - 205943460

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000174502 (version 83.38)

Entrez gene

 115019

UniProt

 Q7LBE3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q7LBE3

Antibodypedia

 SLC26A9 antibodies

PROTEIN BROWSER
SLC26A9-001
SLC26A9-003
SLC26A9-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SLC26A9-001
ENSP00000356103
ENST00000367135
Q7LBE3 [Direct mapping]
Solute carrier family 26 member 9
Show all
Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005254 [chloride channel activity]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006811 [ion transport]
GO:0006820 [anion transport]
GO:0006821 [chloride transport]
GO:0008271 [secondary active sulfate transmembrane transporter activity]
GO:0008272 [sulfate transport]
GO:0009986 [cell surface]
GO:0010628 [positive regulation of gene expression]
GO:0015106 [bicarbonate transmembrane transporter activity]
GO:0015116 [sulfate transmembrane transporter activity]
GO:0015301 [anion:anion antiporter activity]
GO:0015701 [bicarbonate transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016324 [apical plasma membrane]
GO:0019531 [oxalate transmembrane transporter activity]
GO:0019532 [oxalate transport]
GO:0042391 [regulation of membrane potential]
GO:0051117 [ATPase binding]
GO:0051453 [regulation of intracellular pH]
GO:0055085 [transmembrane transport]
GO:0070062 [extracellular exosome]
GO:1902358 [sulfate transmembrane transport]
GO:1902476 [chloride transmembrane transport]
Show all
 791 aa
87 kDa 		No >9
SLC26A9-003
ENSP00000341682
ENST00000340781
Q7LBE3 [Direct mapping]
Solute carrier family 26 member 9
Show all
Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005254 [chloride channel activity]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006811 [ion transport]
GO:0006820 [anion transport]
GO:0006821 [chloride transport]
GO:0008271 [secondary active sulfate transmembrane transporter activity]
GO:0008272 [sulfate transport]
GO:0009986 [cell surface]
GO:0010628 [positive regulation of gene expression]
GO:0015106 [bicarbonate transmembrane transporter activity]
GO:0015116 [sulfate transmembrane transporter activity]
GO:0015301 [anion:anion antiporter activity]
GO:0015701 [bicarbonate transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016324 [apical plasma membrane]
GO:0019531 [oxalate transmembrane transporter activity]
GO:0019532 [oxalate transport]
GO:0042391 [regulation of membrane potential]
GO:0051117 [ATPase binding]
GO:0051453 [regulation of intracellular pH]
GO:0055085 [transmembrane transport]
GO:0070062 [extracellular exosome]
GO:1902358 [sulfate transmembrane transport]
GO:1902476 [chloride transmembrane transport]
Show all
 887 aa
97.3 kDa 		No >9
SLC26A9-201
ENSP00000356102
ENST00000367134
Q7LBE3 [Direct mapping]
Solute carrier family 26 member 9
Show all
Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005254 [chloride channel activity]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006811 [ion transport]
GO:0006820 [anion transport]
GO:0006821 [chloride transport]
GO:0008271 [secondary active sulfate transmembrane transporter activity]
GO:0008272 [sulfate transport]
GO:0009986 [cell surface]
GO:0010628 [positive regulation of gene expression]
GO:0015106 [bicarbonate transmembrane transporter activity]
GO:0015116 [sulfate transmembrane transporter activity]
GO:0015301 [anion:anion antiporter activity]
GO:0015701 [bicarbonate transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016324 [apical plasma membrane]
GO:0019531 [oxalate transmembrane transporter activity]
GO:0019532 [oxalate transport]
GO:0042391 [regulation of membrane potential]
GO:0051117 [ATPase binding]
GO:0051453 [regulation of intracellular pH]
GO:0055085 [transmembrane transport]
GO:0070062 [extracellular exosome]
GO:1902358 [sulfate transmembrane transport]
GO:1902476 [chloride transmembrane transport]
Show all
 887 aa
97.3 kDa 		No >9

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.