Tissue expression of IL20RB - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	IL20RB
Gene description	Interleukin 20 receptor beta
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (skin, esophagus)
GTEx:	Group enriched (skin, esophagus, vagina)
FANTOM5:	Group enriched (esophagus, tonsil, vagina, cervix, uterine)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (skin, esophagus)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (skin, esophagus, vagina)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (esophagus, tonsil, vagina, cervix, uterine)

GENE INFORMATION
Gene name	IL20RB (HGNC Symbol)
Synonyms	DIRS1, FNDC6, IL-20R2, MGC34923
Description	Interleukin 20 receptor beta (HGNC Symbol)
Entrez gene summary	IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20 (IL20; MIM 605619) (Blumberg et al., 2001 [PubMed 11163236]).[supplied by OMIM, Feb 2009]
Chromosome	3
Cytoband	q22.3
Chromosome location (bp)	136946230 - 137011085
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000174564 (version 83.38)
Entrez gene	53833
UniProt	Q6UXL0 (UniProt - Evidence at protein level)
neXtProt	NX_Q6UXL0
Antibodypedia	IL20RB antibodies

PROTEIN BROWSER

IL20RB-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
IL20RB-001 ENSP00000328133 ENST00000329582	Q6UXL0 [Direct mapping] Interleukin-20 receptor subunit beta Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0001808 [negative regulation of type IV hypersensitivity] GO:0002437 [inflammatory response to antigenic stimulus] GO:0002765 [immune response-inhibiting signal transduction] GO:0004896 [cytokine receptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0019221 [cytokine-mediated signaling pathway] GO:0032689 [negative regulation of interferon-gamma production] GO:0032703 [negative regulation of interleukin-2 production] GO:0032733 [positive regulation of interleukin-10 production] GO:0032753 [positive regulation of interleukin-4 production] GO:0042015 [interleukin-20 binding] GO:0042130 [negative regulation of T cell proliferation] GO:0048873 [homeostasis of number of cells within a tissue] GO:0050863 [regulation of T cell activation] Show all	311 aa 35.1 kDa	No	1