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NPAS4

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GENERAL INFORMATION

Gene name

 NPAS4

Gene description

 Neuronal PAS domain protein 4

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Not detected

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 NPAS4 (HGNC Symbol)

Synonyms

 bHLHe79, Le-PAS, NXF, PASD10

Description

 Neuronal PAS domain protein 4 (HGNC Symbol)

Entrez gene summary

 NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008]

Chromosome

 11

Cytoband

 q13.2

Chromosome location (bp)

 66421004 - 66426707

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000174576 (version 83.38)

Entrez gene

 266743

UniProt

 Q8IUM7 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8IUM7

Antibodypedia

 NPAS4 antibodies

PROTEIN BROWSER
NPAS4-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NPAS4-001
ENSP00000311196
ENST00000311034
Q8IUM7 [Direct mapping]
Neuronal PAS domain-containing protein 4
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Show all
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0001012 [RNA polymerase II regulatory region DNA binding]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005667 [transcription factor complex]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0060080 [inhibitory postsynaptic potential]
GO:0071386 [cellular response to corticosterone stimulus]
Show all
 802 aa
87.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.