Expression of B4GAT1 in cancer - Summary

CANCER ATLAS

Gene description

Beta-1,4-glucuronyltransferase 1

Protein class

Disease related genes, Plasma proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA015484

GENE INFORMATION
Gene name	B4GAT1 (HGNC Symbol)
Synonyms	B3GN-T1, B3GNT1, B3GNT6, BETA3GNTI, iGAT, iGNT
Description	Beta-1,4-glucuronyltransferase 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It is essential for the synthesis of poly-N-acetyllactosamine, a determinant for the blood group i antigen. [provided by RefSeq, Jul 2008]
Chromosome	11
Cytoband	q13.2
Chromosome location (bp)	66345372 - 66347692
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000174684 (version 83.38)
Entrez gene	11041
UniProt	O43505 (UniProt - Evidence at protein level)
neXtProt	NX_O43505
Antibodypedia	B4GAT1 antibodies

PROTEIN BROWSER

B4GAT1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
B4GAT1-001 ENSP00000309096 ENST00000311181	O43505 [Direct mapping] Beta-1,4-glucuronyltransferase 1 A0A024R5F9 [Target identity:100%; Query identity:100%] UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6, isoform CRA_a Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005794 [Golgi apparatus] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0007411 [axon guidance] GO:0008532 [N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity] GO:0015020 [glucuronosyltransferase activity] GO:0018146 [keratan sulfate biosynthetic process] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0030311 [poly-N-acetyllactosamine biosynthetic process] GO:0035269 [protein O-linked mannosylation] GO:0042339 [keratan sulfate metabolic process] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0070062 [extracellular exosome] Show all	415 aa 47.1 kDa	Yes	0