Tissue expression of C4orf26 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	C4orf26
Gene description	Chromosome 4 open reading frame 26
Protein class	Disease related genes Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (placenta)
GTEx:	Not detected
FANTOM5:	Tissue enriched (placenta)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (placenta)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Not detected
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (placenta)

GENE INFORMATION
Gene name	C4orf26 (HGNC Symbol)
Synonyms	FLJ23657
Description	Chromosome 4 open reading frame 26 (HGNC Symbol)
Entrez gene summary	Dental enamel forms the outer cap of teeth and is the hardest substance found in vertebrates. This gene is thought to encode an extracellular matrix acidic phosphoprotein that has a function in enamel mineralization during amelogenesis. Mutations in this gene are associated with recessive hypomineralized amelogenesis imperfecta. [provided by RefSeq, Oct 2012]
Chromosome	4
Cytoband	q21.1
Chromosome location (bp)	75556048 - 75565885
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000174792 (version 83.38)
Entrez gene	152816
UniProt	Q17RF5 (UniProt - Evidence at protein level)
neXtProt	NX_Q17RF5
Antibodypedia	C4orf26 antibodies

PROTEIN BROWSER

C4orf26-001	C4orf26-004	C4orf26-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C4orf26-001 ENSP00000311307 ENST00000311623	Q17RF5 [Direct mapping] Uncharacterized protein C4orf26 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Disease related genes Show all	GO:0005515 [protein binding] GO:0005576 [extracellular region] Show all	130 aa 15.6 kDa	Yes	0
C4orf26-004 ENSP00000406925 ENST00000435974	Q17RF5 [Direct mapping] Uncharacterized protein C4orf26 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Disease related genes Show all	GO:0005515 [protein binding] GO:0005576 [extracellular region] Show all	176 aa 20.4 kDa	Yes	0
C4orf26-201 ENSP00000479147 ENST00000616557	A0A087WV33 [Direct mapping] Uncharacterized protein; Uncharacterized protein C4orf26 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		85 aa 9.7 kDa	Yes	0