Expression of DNAH12 in cancer - Summary

CANCER ATLAS

Gene description

Dynein, axonemal, heavy chain 12

Protein class

Cancer-related genes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA037493	HPA058203	HPA061365

GENE INFORMATION
Gene name	DNAH12 (HGNC Symbol)
Synonyms	DHC3, DLP12, DNAH12L, DNAH7L, Dnahc3, DNHD2, FLJ40427, FLJ44290, hdhc3, HL-19
Description	Dynein, axonemal, heavy chain 12 (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	p14.3
Chromosome location (bp)	57293699 - 57544344
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000174844 (version 83.38)
Entrez gene	201625
UniProt	Q6ZR08 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6ZR08
Antibodypedia	DNAH12 antibodies

PROTEIN BROWSER

DNAH12-002	DNAH12-003	DNAH12-005	DNAH12-201	DNAH12-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DNAH12-002 ENSP00000374187 ENST00000389536	J3QTM1 [Direct mapping] Dynein heavy chain 12, axonemal Show all	Predicted intracellular proteins Cancer-related genes Mutated cancer genes Show all	GO:0003777 [microtubule motor activity] GO:0007018 [microtubule-based movement] GO:0008152 [metabolic process] Show all	784 aa 91.7 kDa	No	0
DNAH12-003 ENSP00000418137 ENST00000495027	E9PG32 [Direct mapping] Dynein heavy chain 12, axonemal Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Cancer-related genes Mutated cancer genes Show all	GO:0003777 [microtubule motor activity] GO:0005524 [ATP binding] GO:0007018 [microtubule-based movement] GO:0008152 [metabolic process] GO:0016887 [ATPase activity] GO:0030286 [dynein complex] Show all	3960 aa 454.3 kDa	No	0
DNAH12-005 ENSP00000420359 ENST00000466540	H7C5N3 [Direct mapping] Dynein heavy chain 12, axonemal Show all	Predicted intracellular proteins Cancer-related genes Mutated cancer genes Show all	GO:0003777 [microtubule motor activity] GO:0007018 [microtubule-based movement] GO:0008152 [metabolic process] GO:0030286 [dynein complex] Show all	740 aa 84.7 kDa	No	0
DNAH12-201 ENSP00000312554 ENST00000311202	Q6ZR08 [Direct mapping] Dynein heavy chain 12, axonemal Show all	Predicted intracellular proteins Cancer-related genes Mutated cancer genes Show all	GO:0003777 [microtubule motor activity] GO:0005524 [ATP binding] GO:0005737 [cytoplasm] GO:0005874 [microtubule] GO:0005929 [cilium] GO:0007018 [microtubule-based movement] GO:0008152 [metabolic process] GO:0016887 [ATPase activity] GO:0030286 [dynein complex] Show all	457 aa 52.7 kDa	No	0
DNAH12-202 ENSP00000295937 ENST00000351747	Q6ZR08 [Direct mapping] Dynein heavy chain 12, axonemal Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Cancer-related genes Mutated cancer genes Show all	GO:0003777 [microtubule motor activity] GO:0005524 [ATP binding] GO:0005737 [cytoplasm] GO:0005874 [microtubule] GO:0005929 [cilium] GO:0007018 [microtubule-based movement] GO:0008152 [metabolic process] GO:0016887 [ATPase activity] GO:0030286 [dynein complex] Show all	3092 aa 356.9 kDa	No	0