Tissue expression of ZG16 - Summary - The Human Protein Atlas

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ZG16

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TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ZG16
Gene description	Zymogen granule protein 16
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (rectum, colon, small intestine)
GTEx:	Group enriched (small intestine, colon)
FANTOM5:	Tissue enhanced (small intestine, colon, appendix)

Protein evidence

Evidence at protein level

Protein expression

Highly selective cytoplasmic expression in mucin-producing goblet cells of the gastrointestinal tract.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA052066 , HPA052512
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (rectum, colon, small intestine)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (small intestine, colon)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (small intestine, colon, appendix)

GENE INFORMATION
Gene name	ZG16 (HGNC Symbol)
Synonyms	hZG16, JCLN, JCLN1, ZG16A
Description	Zymogen granule protein 16 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p11.2
Chromosome location (bp)	29778240 - 29782973
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000174992 (version 83.38)
Entrez gene	653808
UniProt	O60844 (UniProt - Evidence at protein level)
neXtProt	NX_O60844
Antibodypedia	ZG16 antibodies

PROTEIN BROWSER

ZG16-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZG16-001 ENSP00000383563 ENST00000400752	O60844 [Direct mapping] Zymogen granule membrane protein 16 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005578 [proteinaceous extracellular matrix] GO:0005796 [Golgi lumen] GO:0015031 [protein transport] GO:0030246 [carbohydrate binding] GO:0031012 [extracellular matrix] GO:0042589 [zymogen granule membrane] GO:0060205 [cytoplasmic membrane-bounded vesicle lumen] Show all	167 aa 18.1 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.