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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

ANTIBODY PRIMARY DATA

Antibodies in assay

HPA023559 , HPA023564 , HPA044971 , CAB031916
 

Tissue presentation order  

Organ
Cell type
Alphabetical
 

Tissue

Antibody staining

Annotated protein expression

HPA023559

HPA023564

HPA044971

CAB031916

h
m
l
n
h
m
l
n
h
m
l
n
h
m
l
n
h
m
l
n
Brain
Cerebral cortex Neuronal cells
Cerebral cortex Endothelial cells
Cerebral cortex Glial cells
Cerebral cortex Neuropil
Hippocampus Neuronal cells
Hippocampus Glial cells
Caudate Neuronal cells
Caudate Glial cells
Cerebellum Purkinje cells
Cerebellum Cells in granular layer
Cerebellum Cells in molecular layer
Endocrine tissues
Thyroid gland Glandular cells
Parathyroid gland Glandular cells
Adrenal gland Glandular cells
Bone marrow & immune system
Appendix Glandular cells
Appendix Lymphoid tissue
N/A
N/A
Bone marrow Hematopoietic cells
N/A
N/A
Lymph node Germinal center cells
N/A
Lymph node Non-germinal center cells
Tonsil Germinal center cells
Tonsil Non-germinal center cells
Tonsil Squamous epithelial cells
Spleen Cells in white pulp
Spleen Cells in red pulp
Muscle tissues
Heart muscle Myocytes
Skeletal muscle Myocytes
Smooth muscle Smooth muscle cells
Respiratory system
Nasopharynx Respiratory epithelial cells
Bronchus Respiratory epithelial cells
Lung Pneumocytes
Lung Macrophages
Liver & gallbladder
Liver Hepatocytes
Liver Bile duct cells
Gallbladder Glandular cells
Pancreas
Pancreas Exocrine glandular cells
Pancreas Islets of Langerhans
Gastrointestinal tract
Oral mucosa Squamous epithelial cells
N/A
Salivary gland Glandular cells
Esophagus Squamous epithelial cells
Stomach 1 Glandular cells
Stomach 2 Glandular cells
Duodenum Glandular cells
Small intestine Glandular cells
Colon Endothelial cells
Colon Glandular cells
Colon Peripheral nerve/ganglion
Rectum Glandular cells
Kidney & urinary bladder
Kidney Cells in glomeruli
Kidney Cells in tubules
Urinary bladder Urothelial cells
Male reproductive system
Testis Cells in seminiferous ducts
Testis Leydig cells
Epididymis Glandular cells
Prostate Glandular cells
Seminal vesicle Glandular cells
Breast and female reproductive system
Breast Adipocytes
Breast Glandular cells
Breast Myoepithelial cells
Vagina Squamous epithelial cells
Cervix, uterine Squamous epithelial cells
N/A
N/A
N/A
Cervix, uterine Glandular cells
Endometrium 1 Glandular cells
Endometrium 1 Cells in endometrial stroma
Endometrium 2 Glandular cells
Endometrium 2 Cells in endometrial stroma
Fallopian tube Glandular cells
Ovary Follicle cells
N/A
N/A
N/A
N/A
Ovary Ovarian stroma cells
Placenta Trophoblastic cells
Placenta Decidual cells
Adipose & soft tissue
Soft tissue 1 Adipocytes
Soft tissue 1 Peripheral nerve
N/A
Soft tissue 1 Chondrocytes
N/A
N/A
N/A
Soft tissue 1 Fibroblasts
N/A
Soft tissue 2 Adipocytes
Soft tissue 2 Fibroblasts
Soft tissue 2 Chondrocytes
N/A
N/A
N/A
Soft tissue 2 Peripheral nerve
Skin
Skin 1 Fibroblasts
Skin 1 Keratinocytes
Skin 1 Langerhans
Skin 1 Melanocytes
Skin 2 Epidermal cells
 

Staining summary

HPA023559 Most of the normal tissues displayed weak to moderate cytoplasmic positivity. Strong staining was observed in exocrine pancreas, placenta, Purkinje cells and a subset of lymphoid cells outside reaction centra.
HPA023564 Most normal cells showed weak to moderate cytoplasmic staining combined with membranous positivity in a few cases. Strong immunoreactivity was observed in a subset of lymphoid cells while the liver were negative.
HPA044971 Normal tissues displayed weak to moderate cytoplasmic positivity. Myocytes and Purkinje cells displayed strong cytoplasmic staining. Lymphoid tissue, islets of Langerhans, pneumocytes, trophoblastic cells and prostate were negative.
CAB031916 Most normal tissues showed weak to moderate nuclear positivity. Decidual cells, subsets of alveolar cells, gall bladder, large intestine and upper glandular cells of stomach showed strong nuclear immunoreactivity. The liver, cells of CNS, myocytes and most lymphoid cells were negative. Malignant cells were generally negative or weakly stained.
 

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